Combination Analgesic Efficacy

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Presentation transcript:

Combination Analgesic Efficacy Jayne E Edwards, DPhil, Henry J McQuay, DM, R.Andrew Moore, DSc  Journal of Pain and Symptom Management  Volume 23, Issue 2, Pages 121-130 (February 2002) DOI: 10.1016/S0885-3924(01)00404-3

Fig. 1 Mean pain relief score over time in dental pain. Journal of Pain and Symptom Management 2002 23, 121-130DOI: (10.1016/S0885-3924(01)00404-3)

Fig. 2 Number-needed-to-treat to obtain at least 50% pain relief with single-dose oral analgesics compared with placebo in moderate to severe postoperative pain over 6 hours. Information was from trials of tramadol plus acetaminophen. Journal of Pain and Symptom Management 2002 23, 121-130DOI: (10.1016/S0885-3924(01)00404-3)

Fig. 3 Number-needed-to-treat to obtain at least 50% pain relief over 4–6 hours. Comparison of single-dose oral tramadol and tramadol plus acetaminophen with other combination drugs and their components. Additional information was from published systematic reviews. Journal of Pain and Symptom Management 2002 23, 121-130DOI: (10.1016/S0885-3924(01)00404-3)