Phenol block of peripheral nerve conduction: Titrating for optimum effect Duk Hyun Sung, MD, Tai Ryoon Han, MD, Won-Hah Park, MD, Heui Je Bang, MD, Jong-Moon.

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Phenol block of peripheral nerve conduction: Titrating for optimum effect Duk Hyun Sung, MD, Tai Ryoon Han, MD, Won-Hah Park, MD, Heui Je Bang, MD, Jong-Moon Kim, MD, Seung-Hyun Chung, MD, Eung-Je Woo, PhD Archives of Physical Medicine and Rehabilitation Volume 82, Issue 5, Pages 671-676 (May 2001) DOI: 10.1053/apmr.2001.21975 Copyright © 2001 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

Fig. 1 Concentration effect: reduction (mean ± SE) of CMAP amplitude with phenol solutions of 5%, 4%, and 3%. Concentration of groups: ●, Ib (5%); ■, Ic (4%); ▴, Id (3%). Archives of Physical Medicine and Rehabilitation 2001 82, 671-676DOI: (10.1053/apmr.2001.21975) Copyright © 2001 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

Fig. 2 Volume effect: reduction (mean ± SE) of CMAP amplitude with 5% phenol solutions of 0.3, 0.2, and 0.1mL. ●, Ib (0.3mL); ■, Ie (0.3mL); ▴, If (0.1mL). Archives of Physical Medicine and Rehabilitation 2001 82, 671-676DOI: (10.1053/apmr.2001.21975) Copyright © 2001 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

Fig. 3 Representative sections from the tibial nerve showing axonal degeneration 2 weeks after phenol nerve block by perineural injection. Note the extent and location of axonal degeneration. Minimal peripheral degeneration occurred at the distal part of the nerve fascicle; a half-thickness degeneration occurred at the proximal site, which seems to be close to the injection point (×40, hematoxylin and eosin staining). The internal scale bar length is 200μm. Archives of Physical Medicine and Rehabilitation 2001 82, 671-676DOI: (10.1053/apmr.2001.21975) Copyright © 2001 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions