Single-dose extended-release oral azithromycin vs Single-dose extended-release oral azithromycin vs. 3-day azithromycin for the treatment of group A β-haemolytic streptococcal pharyngitis/tonsillitis in adults and adolescents: a double-blind, double-dummy study  D.M. Jorgensen  Clinical Microbiology and Infection  Volume 15, Issue 12, Pages 1103-1110 (December 2009) DOI: 10.1111/j.1469-0691.2009.02718.x Copyright © 2009 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 CONSORT flow diagram for the double-blind, double-dummy study evaluating the azithromycin extended-release formulation (AZ-ER) vs. the immediate-release formulation (AZ-IR). TOC, test-of-cure; BPP, bacteriological per-protocol population; LTFU, long-term follow-up; GABHS, group A β-haemolytic streptococcus. Clinical Microbiology and Infection 2009 15, 1103-1110DOI: (10.1111/j.1469-0691.2009.02718.x) Copyright © 2009 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 2 Rates of (a) bacteriological eradication and (b) clinical cure at test-of-cure (TOC) and continued at long-term follow-up (LTFU) in those subjects with eradication at the TOC visit and cured at the TOC visit, respectively (bacteriological per-protocol population). AZ-ER, azithromycin extended-release formulation; AZ-IR, azithromycin immediate-release formulation. [For the LTFU analyses, evaluable subjects in the bacteriologic per-protocol population also had to be classified as having bacteriological eradication at the TOC visit. Similarly, in Figure 2b, the LTFU evaluable subjects in the bacteriological per-protocol population also had to be classified as having a clinical cure at the TOC visit.] Clinical Microbiology and Infection 2009 15, 1103-1110DOI: (10.1111/j.1469-0691.2009.02718.x) Copyright © 2009 European Society of Clinical Infectious Diseases Terms and Conditions