AJKD Atlas of Renal Pathology: Chronic Antibody-Mediated Rejection Behzad Najafian, MD, Agnes B. Fogo, MD, Mark A. Lusco, MD, Charles E. Alpers, MD  American Journal of Kidney Diseases  Volume 66, Issue 5, Pages e41-e42 (November 2015) DOI: 10.1053/j.ajkd.2015.08.008 Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions

Figure 1 Transplant glomerulopathy with prominent global glomerular basement membrane duplication. A few capillary loops show glomerulitis with increased intracapillary leukocytes (Jones silver stain). American Journal of Kidney Diseases 2015 66, e41-e42DOI: (10.1053/j.ajkd.2015.08.008) Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions

Figure 2 Transplant glomerulopathy with prominent glomerular basement membrane duplication and cellular interposition in a capillary loop. Podocytes show significant foot process effacement (electron microscopy). American Journal of Kidney Diseases 2015 66, e41-e42DOI: (10.1053/j.ajkd.2015.08.008) Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions

Figure 3 Chronic antibody-mediated rejection with severe peritubular capillary multilayering (>7 layers of basement membrane), representing response to repetitive and chronic endothelial injury. Note that the endothelial cell is swollen and has lost its normal fenestrations (electron microscopy). American Journal of Kidney Diseases 2015 66, e41-e42DOI: (10.1053/j.ajkd.2015.08.008) Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions

Figure 4 Chronic antibody-mediated rejection with diffuse linear C4d staining in peritubular capillaries (immunofluorescence microscopy, C4d). American Journal of Kidney Diseases 2015 66, e41-e42DOI: (10.1053/j.ajkd.2015.08.008) Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions