A comparison of the effects of N-acetylcysteine and ethyl pyruvate on experimental testicular ischemia-reperfusion injury Suha Turkmen, M.D., Ahmet Mentese,

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A comparison of the effects of N-acetylcysteine and ethyl pyruvate on experimental testicular ischemia-reperfusion injury Suha Turkmen, M.D., Ahmet Mentese,

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A comparison of the effects of N-acetylcysteine and ethyl pyruvate on experimental testicular ischemia-reperfusion injury Suha Turkmen, M.D., Ahmet Mentese, Ph.D., Ersagun Karaguzel, M.D., Yunus Karaca, M.D., Adem Kucuk, M.D., Aysegul Uzun, Ph.D., Esin Yulug, M.D., Suleyman Turedi, M.D. Fertility and Sterility Volume 98, Issue 3, Pages 626-631 (September 2012) DOI: 10.1016/j.fertnstert.2012.05.034 Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Schematic diagram of the interventions in each study group. EP = ethyl pyruvate; NAC = N-acetylcysteine; T/D = torsion and detorsion. Fertility and Sterility 2012 98, 626-631DOI: (10.1016/j.fertnstert.2012.05.034) Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions

Figure 2 (A) Normal testicular tubule histopathological structure in the control group (↑). (B) Spermatogenetic cells in the testicular tissue seminiferous tubular lumen in the torsion/detorsion group (↑), injury in the tubular epithelium (▴). (C) Normal seminiferous tubular structure in the ethyl pyruvate group testicular structure (↑). (D) Normal seminiferous tubular structure in N-acetylcysteine group testicular tissue (↑) and spermatozoa in the tubular lumen (▴). (Hematoxylin and eosin [H & E], ×200.) Fertility and Sterility 2012 98, 626-631DOI: (10.1016/j.fertnstert.2012.05.034) Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions

Figure 3 Serum ischemia-modified albumin (IMA) levels in all groups. ABSU = absorbance unit; EP = ethyl pyruvate; NAC = N-acetylcysteine; T/D = torsion and detorsion. Fertility and Sterility 2012 98, 626-631DOI: (10.1016/j.fertnstert.2012.05.034) Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions