Genetic influence on cytokine production in meningococcal disease

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Genetic influence on cytokine production in meningococcal disease RGJ Westendorp, JAM Langermans, TWJ Huizinga, CL Verweij, A Sturk The Lancet Volume 349, Issue 9069, Pages 1912-1913 (June 1997) DOI: 10.1016/S0140-6736(05)63910-4 Copyright © 1997 Elsevier Ltd Terms and Conditions

Figure Production of tumour necrosis factor-alpha (TNF) and interleukin-10 in 39 healthy volunteers Production of TNF-α was measured by ELISA in samples of whole blood after 4 h incubation with 1000 ng/mL endotoxin. Interleukin-10 was measured after 24 h incubation. Production of the two cytokines was not correlated (r=0·20, p=0·22). The Lancet 1997 349, 1912-1913DOI: (10.1016/S0140-6736(05)63910-4) Copyright © 1997 Elsevier Ltd Terms and Conditions