Franklin SS, et al. Circulation 2009;119:243-50

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Presentation transcript:

Franklin SS, et al. Circulation 2009;119:243-50

Descriptive and Baseline Characteristics of Framingham Original and Offspring Cohort Franklin SS, et al. Circulation 2009;119:243-50

Frequency Distribution of CVD Events per Number of Person-Observations by SBP and DBP Groups Franklin SS, et al. Circulation 2009;119:243-50

ORs (95% CIs)* for CVD Events Based on Cross-Classification of SBP and DBP Groups Franklin SS, et al. Circulation 2009;119:243-50

Likelihood Ratio Test and Receiver Operating Characteristic Analysis Comparing BP Models in Predicting CVD Franklin SS, et al. Circulation 2009;119:243-50

Odds for the likelihood of a cardiovascular event with combined SBP and DBP categories in a 6x6 cross-classification bar graph, adjusted for age, sex, total cholesterol, smoking, body mass index, diabetes, and secular trend. An interaction term of SBPxDBP improved the model fit (Δ 2=35.9; P=0.02) Franklin SS, et al. Circulation 2009;119:243-50

Frequency Distribution of CVD Events per Number of Person-Observations by PP and MAP Groups Franklin SS, et al. Circulation 2009;119:243-50

ORs (95% CIs)* for CVD Events Based on Cross-Classification of PP and MAP Groups Franklin SS, et al. Circulation 2009;119:243-50

Odds for the likelihood of a cardiovascular event with combined PP and MAP categories in a 6x6 cross-classification bar graph, adjusted for age, sex, total cholesterol, smoking, body mass index, diabetes, and secular trend. An interaction term of PPxMAP improved the model fit (Δ  2=43.1; P=0.01) Franklin SS, et al. Circulation 2009;119:243-50

CLINICAL PERSPECTIVE Franklin SS, et al. Circulation 2009;119:243-50