Association and Interaction of the IL4R, IL4, and IL13 Loci with Type 1 Diabetes among Filipinos Teodorica L. Bugawan, Daniel B. Mirel, Ana M. Valdes, Araceli Panelo, Paolo Pozzilli, Henry A. Erlich The American Journal of Human Genetics Volume 72, Issue 6, Pages 1505-1514 (June 2003) DOI: 10.1086/375655 Copyright © 2003 The American Society of Human Genetics Terms and Conditions
Figure 1 Gene-gene interaction. ORs and patient and control counts of specific IL4R and IL4-IL13 genotypes are shown. A, IL4R E375A (Glu encoded by the A allele, Ala by the C allele) with IL4 T-524C. B, IL4R Q551R (Gln encoded by the A allele, Arg by the G allele) with IL13 A-1512C. C, IL4R C-3223T and IL13 A-1512C. D, IL4R C-3223T and IL13 C-1112T. The P value for the association of each genotype combination is shown above each OR bar. The American Journal of Human Genetics 2003 72, 1505-1514DOI: (10.1086/375655) Copyright © 2003 The American Society of Human Genetics Terms and Conditions