Is a high tibial osteotomy (HTO) superior to non-surgical treatment in patients with varus malaligned medial knee osteoarthritis (OA)? A propensity matched.

Slides:



Advertisements
Similar presentations
Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis A. Loyola-Sánchez, J. Richardson, N.J.
Advertisements

The association between metacarpal ratio, radiographic hand and knee osteoarthritis and its progression after meniscectomy  P.T. Paradowski, L.S. Lohmander,
Sensitivity and associations with pain and body weight of an MRI definition of knee osteoarthritis compared with radiographic Kellgren and Lawrence criteria:
Knee osteoarthritis radiographic progression and associations with pain and function prior to knee arthroplasty: a multicenter comparative cohort study 
Electrical stimulation for pain relief in knee osteoarthritis: systematic review and network meta-analysis  C. Zeng, H. li, T. Yang, Z.-h. Deng, Y. Yang,
Osteoarthritis and Cartilage
T. E. McAlindon, R. R. Bannuru, M. C. Sullivan, N. K. Arden, F
A statistical model of shape and density of the proximal femur in relation to radiological and clinical OA of the hip  J.H. Waarsing, R.M. Rozendaal,
Electrical stimulation for pain relief in knee osteoarthritis: systematic review and network meta-analysis  C. Zeng, H. li, T. Yang, Z.-h. Deng, Y. Yang,
Pincer deformity does not lead to osteoarthritis of the hip whereas acetabular dysplasia does: acetabular coverage and development of osteoarthritis in.
Short-term placebo response in trials of patients with symptomatic osteoarthritis: differences between hip and knee  S. Reiter-Niesert, M. Boers, J. Detert 
P.-S. Hsu, H.-H. Lin, C.-R. Li, W.-S. Chung 
T. E. McAlindon, R. R. Bannuru, M. C. Sullivan, N. K. Arden, F
OARSI recommendations for the management of hip and knee osteoarthritis, Part I: Critical appraisal of existing treatment guidelines and systematic review.
A. W. A. Baltzer, M. D. , C. Moser, M. D. , S. A. Jansen, M. D. , R
CT arthrography of the human knee to quantitatively measure cartilage biochemical composition: preliminary results of an in-vivo validation study using.
One year effectiveness of neuromuscular exercise compared with instruction in analgesic use on knee function in patients with early knee osteoarthritis:
R. Takeuchi, H. Ishikawa, T. Kuniya, A. Nakazawa 
Influence of flare design on symptomatic efficacy of non-steroidal anti-inflammatory drugs in osteoarthritis: a meta-analysis of randomized placebo-controlled.
Osteoarthritis as a disease of mechanics
No evidence for the effectiveness of a multidisciplinary group based treatment program in patients with osteoarthritis of hands on the short term; results.
Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role.
Pre-operative interventions (non-surgical and non-pharmacological) for patients with hip or knee osteoarthritis awaiting joint replacement surgery – a.
Health-related quality of life and costs in patients with osteoarthritis on waiting list for total knee replacement  M. Núñez, Ph.D., E. Núñez, Ph.D.,
Efficacy and safety of intraarticular hyaluronic acid in the treatment of hip osteoarthritis: a systematic review  J.C. Fernández López, M.D., Ph.D.,
Bone mineral density changes in the knee following anterior cruciate ligament rupture  B.L. van Meer, J.H. Waarsing, W.A. van Eijsden, D.E. Meuffels, E.R.A.
NSAIDs vs acetaminophen in knee and hip osteoarthritis: a systematic review regarding heterogeneity influencing the outcomes  S.P.J. Verkleij, P.A.J.
Brace treatment for osteoarthritis of the knee: a prospective randomized multi-centre trial  R.W. Brouwer, M.D., T.M. van Raaij, M.D., J.A.N. Verhaar,
Statistical shape modelling of the patella: Patients with patellofemoral pain and patellofemoral osteoarthritis share similar aberrant shape aspects compared.
B. F. Riecke, R. Christensen, S. Torp-Pedersen, M. Boesen, H
Sensitivity and associations with pain and body weight of an MRI definition of knee osteoarthritis compared with radiographic Kellgren and Lawrence criteria:
Time to be positive about negative data?
J. Avouac, M.D., L. Gossec, M.D., M. Dougados, M.D. 
The OA Trial Bank: meta-analysis of individual patient data from knee and hip osteoarthritis trials show that patients with severe pain exhibit greater.
Risk factors associated with reduced work productivity among people with chronic knee pain  M. Agaliotis, M. Fransen, L. Bridgett, L. Nairn, M. Votrubec,
J. Ranstam  Osteoarthritis and Cartilage 
The combined efficacy of multimodal non-surgical treatment on pain and sensitization in patients with knee osteoarthritis not eligible for a total knee.
A double-blind randomized controlled trial comparing alternate forms of high molecular weight hyaluronan for the treatment of osteoarthritis of the knee 
OARSI Clinical Trials Recommendations: Design and conduct of implementation trials of interventions for osteoarthritis  K.D. Allen, S.M.A. Bierma-Zeinstra,
A new lipid formulation of low dose (1200mg) ibuprofen is non-inferior to high dose (2400mg) standard ibuprofen capsules in managing episodic knee pain.
The course of limitations in activities over 5 years in patients with knee and hip osteoarthritis with moderate functional limitations: risk factors for.
Osteoarthritis of the knee after meniscal resection: long term radiographic evaluation of disease progression  P.T. Paradowski, L.S. Lohmander, M. Englund 
Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis  M. Blagojevic, C. Jinks, A. Jeffery, K.P.
Preliminary results of a phase II randomized study to determine the efficacy and safety of genetically engineered allogeneic human chondrocytes expressing.
Anxiety and depressive symptoms before and after total hip and knee arthroplasty: a prospective multicentre study  T. Duivenvoorden, M.M. Vissers, J.A.N.
Who should have a joint replacement? A plea for more ‘phronesis’
Pincer deformities and mild acetabular dysplasia: the relationship between acetabular coverage and development of hip OA in the nationwide prospective.
Hip strengthening reduces symptoms but not knee load in people with medial knee osteoarthritis and varus malalignment: a randomised controlled trial 
Safety of intra-articular cell-therapy with culture-expanded stem cells in humans: a systematic literature review  C.M.M. Peeters, M.J.C. Leijs, M. Reijman,
Corrigendum to ‘2014 OARSI Guidelines for the Non-Surgical Management of Knee Osteoarthritis’ [Osteoarthritis and Cartilage 22 (2014) 363–388]  T.E. McAlindon,
Macrophage Phenotypes are Associated With Processes of Osteoarthritis in The Collagenase-Induced Osteoarthritis (CIOA) and Destabilization of The Medial.
D.J. Hunter  Osteoarthritis and Cartilage 
Pain trajectory groups in persons with, or at high risk of, knee osteoarthritis: findings from the Knee Clinical Assessment Study and the Osteoarthritis.
S.G. Muthuri, D.F. McWilliams, M. Doherty, W. Zhang 
Cam impingement: defining the presence of a cam deformity by the alpha angle  R. Agricola, J.H. Waarsing, G.E. Thomas, A.J. Carr, M. Reijman, S.M.A. Bierma-Zeinstra,
Preoperative progressive explosive-type resistance training is feasible and effective in patients with hip osteoarthritis scheduled for total hip arthroplasty.
Instruments to assess physical activity in patients with osteoarthritis of the hip or knee: a systematic review of measurement properties  C.B. Terwee,
Most patients gain weight in the 2 years after total knee arthroplasty: comparison to a healthy control group  J.A. Zeni, L. Snyder-Mackler  Osteoarthritis.
Osteoarthritis and Cartilage
C. Ratzlaff, M. Koehoorn, J. Cibere, J. Kopec 
Development and preliminary evaluation of the OsteoArthritis Questionnaire (OA- Quest): a psychometric study  L. Busija, R. Buchbinder, R.H. Osborne  Osteoarthritis.
Osteoarthritis year 2012 in review: biology
No treatment effects of oral glucosamine for subgroups of knee and hip osteoarthritis patients; an individual patient data meta-analysis from the OA trial.
L.A. Deveza, L. Melo, T.P. Yamato, K. Mills, V. Ravi, D.J. Hunter 
Diclofenac not more effective than acetaminophen in patients with mild knee osteoarthritis: results of a randomized controlled trial in primary care with.
Efficacy of rehabilitation programs for improving muscle strength in people with hip or knee osteoarthritis: a systematic review with meta-analysis  A.
Total hip replacement but not clinical osteoarthritis can be predicted by the shape of the hip: a prospective cohort study (CHECK)  R. Agricola, M. Reijman,
Influence of delayed gadolinium enhanced MRI of cartilage (dGEMRIC) protocol on T2- mapping: is it possible to comprehensively assess knee cartilage composition.
A new lipid formulation of low dose ibuprofen shows non-inferiority to high dose standard ibuprofen: the FLARE study (flaring arthralgia relief evaluation.
General Information Osteoarthritis and Cartilage
Presentation transcript:

Is a high tibial osteotomy (HTO) superior to non-surgical treatment in patients with varus malaligned medial knee osteoarthritis (OA)? A propensity matched study using 2 randomized controlled trial (RCT) datasets  M.V. van Outeren, J.H. Waarsing, R.W. Brouwer, J.A.N. Verhaar, M. Reijman, S.M.A. Bierma-Zeinstra  Osteoarthritis and Cartilage  Volume 25, Issue 12, Pages 1988-1993 (December 2017) DOI: 10.1016/j.joca.2017.09.003 Copyright © 2017 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Flowchart: propensity score one-to-many matching. Osteoarthritis and Cartilage 2017 25, 1988-1993DOI: (10.1016/j.joca.2017.09.003) Copyright © 2017 Osteoarthritis Research Society International Terms and Conditions