A Phase I Study of Pomalidomide (CC-4047) in Combination with Cisplatin and Etoposide in Patients with Extensive-Stage Small-Cell Lung Cancer Peter M.

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Presentation transcript:

A Phase I Study of Pomalidomide (CC-4047) in Combination with Cisplatin and Etoposide in Patients with Extensive-Stage Small-Cell Lung Cancer Peter M. Ellis, MD, PhD, Ulf Jungnelius, MD, Jennie Zhang, PhD, Abderrahim Fandi, MD, PhD, Robert Beck, BSc, Frances A. Shepherd, MD Journal of Thoracic Oncology Volume 8, Issue 4, Pages 423-428 (April 2013) DOI: 10.1097/JTO.0b013e318282707b Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Patient disposition and trial profile. A, Start of 21-day cycle of treatment: cisplatin+etoposide administered intravenously on days 1 to 3 of each cycle; pomalidomide administered orally for 14 consecutive days beginning on day 1. DLT, dose-limiting toxicity; MTD, maximum-tolerated dose; PD, progressive disease. Journal of Thoracic Oncology 2013 8, 423-428DOI: (10.1097/JTO.0b013e318282707b) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions