Effects of Intensive Blood Pressure Treatment on Acute Kidney Injury Events in the Systolic Blood Pressure Intervention Trial (SPRINT) Michael V. Rocco,

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Presentation transcript:

Effects of Intensive Blood Pressure Treatment on Acute Kidney Injury Events in the Systolic Blood Pressure Intervention Trial (SPRINT) Michael V. Rocco, Kaycee M. Sink, Laura C. Lovato, Dawn F. Wolfgram, Thomas B. Wiegmann, Barry M. Wall, Kausik Umanath, Frederic Rahbari-Oskoui, Anna C. Porter, Roberto Pisoni, Cora E. Lewis, Julia B. Lewis, James P. Lash, Lois A. Katz, Amret T. Hawfield, William E. Haley, Barry I. Freedman, Jamie P. Dwyer, Paul E. Drawz, Mirela Dobre, Alfred K. Cheung, Ruth C. Campbell, Udayan Bhatt, Srinivasan Beddhu, Paul L. Kimmel, David M. Reboussin, Glenn M. Chertow American Journal of Kidney Diseases Volume 71, Issue 3, Pages 352-361 (March 2018) DOI: 10.1053/j.ajkd.2017.08.021 Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

American Journal of Kidney Diseases 2018 71, 352-361DOI: (10. 1053/j American Journal of Kidney Diseases 2018 71, 352-361DOI: (10.1053/j.ajkd.2017.08.021) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

Figure 1 CONSORT (Consolidated Standards of Reporting Trials) diagram. Abbreviation: BP, blood pressure. American Journal of Kidney Diseases 2018 71, 352-361DOI: (10.1053/j.ajkd.2017.08.021) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

Figure 2 Cumulative hazard plot for acute kidney injury. Abbreviation: CI, confidence interval. American Journal of Kidney Diseases 2018 71, 352-361DOI: (10.1053/j.ajkd.2017.08.021) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

Figure 3 Forest plot of acute kidney injury. The dashed vertical line represents the hazard ratio for the overall study population. Box sizes are proportional to the precision of the estimates (with larger boxes indicating a greater degree of precision). The subgroup of no previous chronic kidney disease (CKD) includes some participants with unknown CKD status at baseline. Black race includes Hispanic black and black as part of a multiracial identification. Abbreviations: BP, blood pressure; CI, confidence interval; CVD, cardiovascular disease. American Journal of Kidney Diseases 2018 71, 352-361DOI: (10.1053/j.ajkd.2017.08.021) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions