A study of degraded skeletal samples using ForenSeq DNA Signature™ Kit

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Presentation transcript:

A study of degraded skeletal samples using ForenSeq DNA Signature™ Kit E. Almohammed, D. Zgonjanin, A. Iyengar, D. Ballard, L. Devesse, H. Sibte Forensic Science International: Genetics Supplement Series Volume 6, Pages e410-e412 (December 2017) DOI: 10.1016/j.fsigss.2017.09.158 Copyright © 2017 Elsevier B.V. Terms and Conditions

Fig. 1 (A & B) Results of 30-bone samples run on FGx-MiSeq showing a cluster density of 866K/mm2. A total 95% of clusters generated run passed filters, which showed that the reaction was highly successful. The average intensity of the reads was 200000. (C) DNA Profile of a degraded bone sample (DI=13) showing a dropout of 7 auSTR loci using GlobalFiler™ kit. MPS results for various markers from the same sample show high efficacy and enhanced discrimination power of Illumina® ForenSeq™ DNA Signature Prep kit. (D) Phenotype estimation of a Serbian bone sample showing a high prediction for blond hair and blue eyes. The sample was predicted to have an ancestry of Eastern European population correctly. (E) Pie chart showing the Y Haplogroup predictions for the 30 bone and teeth samples using Haplogroup predictor online tool. Forensic Science International: Genetics Supplement Series 2017 6, e410-e412DOI: (10.1016/j.fsigss.2017.09.158) Copyright © 2017 Elsevier B.V. Terms and Conditions