Gene therapy in haematology and oncology

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Presentation transcript:

Gene therapy in haematology and oncology Katherine A High, MD The Lancet Volume 356, (December 2000) DOI: 10.1016/S0140-6736(00)91994-9 Copyright © 2000 Elsevier Ltd Terms and Conditions

The Lancet 2000 356, DOI: (10.1016/S0140-6736(00)91994-9) Copyright © 2000 Elsevier Ltd Terms and Conditions

Principle of ex-vivo and in-vivo gene transfer In ex-vivo gene transfer, recipient cells are removed from the patient, transduced with the vector, and reinfused. For in-vivo approaches, vector is injected directly into the patient. The Lancet 2000 356, DOI: (10.1016/S0140-6736(00)91994-9) Copyright © 2000 Elsevier Ltd Terms and Conditions