Ex Vivo Evaluation of Nonacceptable Donor Lungs

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Ex Vivo Evaluation of Nonacceptable Donor Lungs Per Wierup, MD, PhD, Åsa Haraldsson, MD, PhD, Folke Nilsson, MD, PhD, Leif Pierre, CCP, Henrik Scherstén, MD, PhD, Martin Silverborn, MD, PhD, Trygve Sjöberg, PhD, Ulla Westfeldt, MD, PhD, Stig Steen, MD, PhD  The Annals of Thoracic Surgery  Volume 81, Issue 2, Pages 460-466 (February 2006) DOI: 10.1016/j.athoracsur.2005.08.015 Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Schematic drawing of the ex vivo lung evaluation system. The lungs, placed in the evaluation box, are connected to the perfusion system and a ventilator. End-tidal CO2, pulmonary arterial pressure (PAP), and left atrial pressure (LAP) are measured. The blood coming out from the left atrium is drained to a reservoir (A), passes a centrifugal pump (B), is deoxygenated in an oxygenator (C) provided with a mixture of gases, passes a flow measurement probe (D) and a leukocyte–arterial filter (E), and is then pumped into the pulmonary artery. F indicates oxygen pressure and temperature sensors, and G, the shunt used to prime the system with Steen solution. The Annals of Thoracic Surgery 2006 81, 460-466DOI: (10.1016/j.athoracsur.2005.08.015) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions