Low-power scanning electron microscope image of normal bone

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Presentation transcript:

Low-power scanning electron microscope image of normal bone architecture in the 3rd lumbar vertebra of a 30 year old woman marrow and other cells have been removed to reveal thick, interconnected plates of bone

Low-power scanning electron microscope image of osteoporotic bone architecture in the 3rd lumbar vertebra of a 71 year old woman marrow and other cells have been removed to reveal eroded, fragile rods of bone

Detail of a trabcular bone element eroded by osteoclasts note extensive pitting and fragility of the bone

Detail of a trabcular bone element perforated by osteoclast action note pitting of the bone ‘stalagmite’