Neurohormonal response to left ventricular reconstruction surgery in ischemic cardiomyopathy  Soren Schenk, MD, Patrick M McCarthy, MD, Randall C Starling,

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Presentation transcript:

Neurohormonal response to left ventricular reconstruction surgery in ischemic cardiomyopathy  Soren Schenk, MD, Patrick M McCarthy, MD, Randall C Starling, MD, MPH, Katherine J Hoercher, RN, Melanie D Hail, BSN, Yoshio Ootaki, MD, PhD, Gary S Francis, MD, Kazuyoshi Doi, MD, James B Young, MD, Kiyotaka Fukamachi, MD, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 128, Issue 1, Pages 38-43 (July 2004) DOI: 10.1016/j.jtcvs.2003.11.012

Figure 1 NYHA functional class (mean) before and after surgery (n = 15). Time of postoperative follow-up varied from 3 months (5 patients) to 12 months (10 patients). No difference was observed between groups. NYHA FC, New York Heart Association functional class. The Journal of Thoracic and Cardiovascular Surgery 2004 128, 38-43DOI: (10.1016/j.jtcvs.2003.11.012)

Figure 2 NE, A-II, and PRA profiles before and after surgery (n = 10). Considerable improvements of neurohormones were observed during follow-up. Of note, patient 6 experienced only a modest decrease of norepinephrine, corresponding to an improvement of NYHA class IV before surgery to class III at 1 year after surgery. The Journal of Thoracic and Cardiovascular Surgery 2004 128, 38-43DOI: (10.1016/j.jtcvs.2003.11.012)