Response of Primary Hepatic Amyloidosis to Melphalan and Prednisone: A Case Report and Review of the Literature  MORIE A. GERTZ, M.D., ROBERT A. KYLE, M.D.  Mayo Clinic Proceedings  Volume 61, Issue 3, Pages 218-223 (March 1986) DOI: 10.1016/S0025-6196(12)61853-9 Copyright © 1986 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 1 A, Pretreatment liver biopsy specimen, showing amyloid deposits (arrow). (Congo red; x40.) B, Pretreatment liver biopsy specimen. Note interstitial amorphous deposits disrupting architecture of hepatic cord and lobules (arrow). (Congo red; x400.) C, Electron micrograph, illustrating fibrillar ultrastructure of amyloid deposits (lower left). (x39,000.) D, Pretreatment liver biopsy specimen under polarized light. (Congo red; x250.) E, Posttreatment liver biopsy specimen, showing normal hepatic tissue. (Congo red; x250.) Mayo Clinic Proceedings 1986 61, 218-223DOI: (10.1016/S0025-6196(12)61853-9) Copyright © 1986 Mayo Foundation for Medical Education and Research Terms and Conditions