Bacterial Cell Division: A Swirling Ring to Rule Them All?

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Bacterial Cell Division: A Swirling Ring to Rule Them All? Petra Schwille  Current Biology  Volume 24, Issue 4, Pages R157-R159 (February 2014) DOI: 10.1016/j.cub.2014.01.025 Copyright © 2014 Elsevier Ltd Terms and Conditions

Figure 1 Possible interpretation of FtsA-induced directional dynamics of FtsZ filaments. As the rate of GTP hydrolysis is not altered, and membrane binding is required for FtsZ fragmentation by FtsA, the predominant effect could be the frustration of lateral contacts. This would allow the treadmilling of single filaments to become significant, and render the turnover non-isotropic (left to middle). Fragmentation of bundles could be aided by a strain on FtsZ filaments when targeted to the membrane (right), explaining the delay in FtsA-induced disassembly. Current Biology 2014 24, R157-R159DOI: (10.1016/j.cub.2014.01.025) Copyright © 2014 Elsevier Ltd Terms and Conditions