Lipid Clinic Challenge

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Presentation transcript:

Lipid Clinic Challenge

Who is Vulnerable and Why

JUPITER Increased Incidence of T2D With Rosuvastatin

Hypotheses

T2D Risk Increases With Statin Potency Meta-Analysis of 5 Clinical Trials

WOSCOPS Pravastatin Reduction in LDL-C/Reduced CAD by 30%

Statins and the Development of Diabetes[a,b]

JUPITER Rosuvastatin Therapy and Diabetes Risk[a,b]

Obesity and Metabolic Syndrome

Analysis of 3 Atorvastatin Trials (TNT, SPARCL, and IDEAL)

Don't Just Blame Statins

2013 ACC/AHA Cholesterol Guidelines Statin Initiation Recommendations

REAL-CAD: Primary Endpoint CV Death/MI/Ischemic Stroke/UA

J-PREDICT Primary Outcome: Cumulative Incidence of Diabetes

ABCA1: A Very Important Transmembrane HDL Binding Protein

Pitavastatin: No Elevation in Serum Glucose

Managing Cardiovascular Risk

Hepatic Steatosis and Insulin Resistance

Effects of Pitavastatin on Insulin Sensitivity and Liver Fat

Case Study: Patient With Obesity With Hypertension and Dyslipidemia

Case Study: Patient With Obesity With Hypertension and Dyslipidemia

Many Issues at Play: Education is Needed

It Takes a Team

Abbreviations

Abbreviations (cont)