Hyperkalemia in the Hospital

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Presentation transcript:

Hyperkalemia in the Hospital

Case Study: Patient Presentation @ 1:20 am

Case Study (cont): EKG @ 1:24 am

K+ in the ED

Hyperkalemia Management in ED: ECG Changes

Overview of Temporizing Treatments

Case Study (cont): Options @ 2:50 am

Hyperkalemia Management in ED: Reassessment of Patient

SPS[a]

Rapid Correction of Hyperkalemia Reduces Mortality in ED

REVEAL-ED

REVEAL-ED: Hyperkalemia Treatment Patterns in the ED

REVEAL-ED: Recordable Outcomes*

REVEAL-ED: K+ Levels From Start of Treatment

"Novel" Potassium Binders

Treatment of Hyperkalemia in the ED: Pilot Study

Results of Hyperkalemia Treatment in ED With Patiromer

New Treatments: ZS-9 Crystal Structure

ZS-9 Clinical Development Programme

Potassium Levels Decrease Within 1 to 4 Hours After First Dose of ZS-9 in Severe Hyperkalemia

Existing Studies Suggest Differences in the Onset of Action of Patiromer and ZS-9, Though There Are No Head-to-Head Trials

Take-Home Messages

Abbreviations

Abbreviations (cont)