Effect of 50 g lactose on breath hydrogen in the three principal genetic groups. Effect of 50 g lactose on breath hydrogen in the three principal genetic.

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Presentation transcript:

Effect of 50 g lactose on breath hydrogen in the three principal genetic groups. Effect of 50 g lactose on breath hydrogen in the three principal genetic groups. Breath hydrogen was measured every 30 minutes after ingesting 50 g oral lactose. The results represent an example of three adults all diagnosed clinically as lactose intolerant. Boxes represents CC/GG lactase non-persistent genotype, breath hydrogen >20 ppm above the nadir at 30 minutes and continues throughout the testing period. Triangles represent CT/GA heterozygous lactase persistent genotype showing a rise in breath hydrogen >20 ppm above the nadir after sampling above 300 minutes. Diamonds represent TT/AA homozygous lactase persistent genotyped patient in which the breath hydrogen does not rise above 20 ppm throughout the testing period of 360 minutes. S B Matthews et al. Postgrad Med J 2005;81:167-173 Copyright © The Fellowship of Postgraduate Medicine. All rights reserved.