The immunophenotype of antigen presenting cells of the mononuclear phagocyte system in normal human liver – A systematic review  Otto Strauss, P. Rod Dunbar, Adam Bartlett, Anthony Phillips  Journal of Hepatology  Volume 62, Issue 2, Pages 458-468 (February 2015) DOI: 10.1016/j.jhep.2014.10.006 Copyright © 2014 European Association for the Study of the Liver Terms and Conditions

Fig. 1 Postulated ontogeny of liver antigen presenting subsets. Liver macrophages can broadly be defined as monocyte derived macrophages or self-replicating yolk-sac derived macrophages. The point at which a monocyte becomes a macrophage is not clearly defined. Liver dendritic cells (DCs) also contain a population of monocyte derived cells, these are important in inflammatory states. Liver DCs are also derived from immature blood dendritic cells that develop from a dendritic cell precursor. HSC, haematopoietic stem cell; LMPP, lymphoid-primed multipotent progenitor; CMP, common myeloid progenitor; MDP, macrophage and DC progenitor; CDP, common dendritic cell precursor; pDC, plasmacytoid dendritic cell. Journal of Hepatology 2015 62, 458-468DOI: (10.1016/j.jhep.2014.10.006) Copyright © 2014 European Association for the Study of the Liver Terms and Conditions

Fig. 2 Quorum. Quorum diagram of results. Journal of Hepatology 2015 62, 458-468DOI: (10.1016/j.jhep.2014.10.006) Copyright © 2014 European Association for the Study of the Liver Terms and Conditions

Journal of Hepatology 2015 62, 458-468DOI: (10. 1016/j. jhep. 2014. 10 Copyright © 2014 European Association for the Study of the Liver Terms and Conditions