LESSON 1 INTNRODUCTION HYE-JOO KWON, Ph.D /

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LESSON 1 INTNRODUCTION HYE-JOO KWON, Ph.D. 1.932 / xhjkwon@hotmail.com BIOINFORMATICS LESSON 1 INTNRODUCTION HYE-JOO KWON, Ph.D. 1.932 / xhjkwon@hotmail.com

“BIOINFORMATICS”?

The science of information. BIOINFORMATICS BIOLOGY + INFORMATICS The science of information. computer science, human-computer interaction, information science, information technology, algorithms & mathematics a broad academic field encompassing computer science, human-computer interaction, information science, information technology, algorithms, areas of mathematics (especially mathematical logic and category theory), and social sciences that are involved

Probably, you’ve learned this from MB.

Molecular Biology as an Information Science “Transfer of sequential information”

Information flow in Biological System Central paradigm for bioinformatics

Biology & Computer science? Huge amount of Biological Data have to be stored, analyzed, and retrieved-tasks that are managed with computers.

What is Bioinformatics? Interface of Biology and Computers The application of computer-based technique in the biological sciences. The use of computers to collect, analyze, and interpret biological information. nucleic acid sequence protein sequences

GENOME TRANSCRIPTOME PROTEOME

DNA sequence ↓ protein sequence protein structure protein function phenotype

“Bioinformatics for Biologists” The primary goal of bioinformatics is to increase the understanding of biological processes. Bioinformatics can be seen as a tool that the biologist needs to use. A set of software tools for molecular sequence analysis! Computational branch of molecular biology

What Bioinformatics can do for you? Searching biological databases Comparing sequences Looking at protein structures Asking biological and biomedical questions with a computer What Bioinformatics can do for you?

For this course, Computer Internet connection Molecular biology background

Many programs can be used online, via the Internet. In most instances, the information and software are freely available.

textbooks 위트레흐트

http://bioinfo. tmmu. edu http://bioinfo.tmmu.edu.cn/downloads/common/upload/files/BioinformaticsandGenomics(EnglishEdition).pdf

http://theory.bio.uu.nl/BPA/tb.pdf

Bioinformatics Portals NCBI (http://www.ncbi.nlm.nih.gov/) EBI (http://www.ebi.ac.uk/) ExPASy (http://www.expasy.org/)

interdisciplinary field that develops and improves upon methods for storing, retrieving, organizing and analyzing biological data. BIOINFORMATICS

BIOINFORMATICS Genome Analysis Sequence Analysis Phylogenetics Structure Bioinformatics Gene Expression System Biology Bioimage Informatics BIOINFORMATICS