Loaded versus unloaded magnetic resonance imaging (MRI) of the knee: Effect on meniscus extrusion in healthy volunteers and patients with osteoarthritis 

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Loaded versus unloaded magnetic resonance imaging (MRI) of the knee: Effect on meniscus extrusion in healthy volunteers and patients with osteoarthritis  Rina Patel, Matthew Eltgroth, Richard B. Souza, Chiyuan A. Zhang, Sharmila Majumdar, Thomas M. Link, Daria Motamedi  European Journal of Radiology Open  Volume 3, Pages 100-107 (January 2016) DOI: 10.1016/j.ejro.2016.05.002 Copyright © 2016 The Authors Terms and Conditions

Fig. 1 MRI-compatible axial loading device. (a) For unloaded imaging, the subject is in neutral position with the leg extended. (b) For loaded imaging, hanging weights equaling half of the patient’s body weight are applied to the frame that. The force of the weight is transmitted through a series of pulleys to the patient’s foot. European Journal of Radiology Open 2016 3, 100-107DOI: (10.1016/j.ejro.2016.05.002) Copyright © 2016 The Authors Terms and Conditions

Fig. 2 Method of meniscus extrusion measurement. The distance from the outermost aspect of the tibial plauteau articular cartilage (solid line) to the outermost edge of the body of the meniscus (dashed line) was measured and reported in mm. European Journal of Radiology Open 2016 3, 100-107DOI: (10.1016/j.ejro.2016.05.002) Copyright © 2016 The Authors Terms and Conditions

Fig. 3 52-year-old female with KL score of 1. These images show increased measurement of medial meniscus extrusion from (a) unloaded to (b) loaded conditions. With loading, there is increase in medial meniscus extrusion. European Journal of Radiology Open 2016 3, 100-107DOI: (10.1016/j.ejro.2016.05.002) Copyright © 2016 The Authors Terms and Conditions

Fig. 4 59-year-old female with KL score of 1. There is no significant change in the lateral meniscus under (a) unloaded and (b) loaded conditions. No significant difference in meniscus position is noted. European Journal of Radiology Open 2016 3, 100-107DOI: (10.1016/j.ejro.2016.05.002) Copyright © 2016 The Authors Terms and Conditions

Fig. 5 69-year-old female with KL score 2. There is increased medial meniscus extrusion under (a) unloaded and (b) loaded conditions. The medial meniscus in this subject was torn. The torn meniscus is more extruded with loading. European Journal of Radiology Open 2016 3, 100-107DOI: (10.1016/j.ejro.2016.05.002) Copyright © 2016 The Authors Terms and Conditions

Fig. 6 Comparison of unloading and loading on the medial meniscus for subjects with increasing KL score. This series of images shows the medial meniscus under unloaded (left column) and loaded (right column) conditions. The subject in the top row has KL Score of 0, followed by 1, 2, 3 and KL score of 4 in the bottom row. All subjects show some increase in medial meniscus extrusion. Although the difference in unloading versus loading seems more apparent with higher KL score versus lower KL score in this group of subjects, no statistically significant difference was noted in the study population. European Journal of Radiology Open 2016 3, 100-107DOI: (10.1016/j.ejro.2016.05.002) Copyright © 2016 The Authors Terms and Conditions