The spectrum of androgen excess disorders

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Presentation transcript:

The spectrum of androgen excess disorders Enrico Carmina, M.D.  Fertility and Sterility  Volume 85, Issue 6, Pages 1582-1585 (June 2006) DOI: 10.1016/j.fertnstert.2006.02.069 Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions

FIGURE 1 Prevalence (%) of different androgen excess disorders among patients with clinical hyperandrogenism (idiopathic hyperandrogenism blue, idiopathic hirsutism aqua, nonclassic 21-OH deficiency yellow, ovulatory PCOS fuchsia, and PCOS red). Modified from Carmina et al. (7). Carmina. Main hyperandrogenic disorders. Fertil Steril 2006. Fertility and Sterility 2006 85, 1582-1585DOI: (10.1016/j.fertnstert.2006.02.069) Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions

FIGURE 2 Mean body mass index (BMI) in normal women (yellow) and hyperandrogenic patients (idiopathic hyperandrogenism blue, ovulatory PCOS fuchsia, and PCOS red). Modified from Carmina et al. (6). **P<.01 vs. normal controls, patients with idiopathic hyperandrogenism, and patients with ovulatory PCOS. Carmina. Main hyperandrogenic disorders. Fertil Steril 2006. Fertility and Sterility 2006 85, 1582-1585DOI: (10.1016/j.fertnstert.2006.02.069) Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions

FIGURE 3 Fasting serum insulin (A) and insulin sensitivity (by QUICKI [1/log Insulin + log Glucose] (B) in normal women (yellow) and hyperandrogenic patients (idiopathic hyperandrogenism blue, ovulatory PCOS fuchsia, and PCOS red). Modified from Carmina et al. (6). *P<.01 vs. normal controls; °P<.01 vs. patients with idiopathic hyperandrogenism; ̂P<.01 vs. patients with ovulatory PCOS. Carmina. Main hyperandrogenic disorders. Fertil Steril 2006. Fertility and Sterility 2006 85, 1582-1585DOI: (10.1016/j.fertnstert.2006.02.069) Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions

FIGURE 4 Fasting serum HDL-cholesterol (A) and triglycerides (B) in normal women (yellow) and hyperandrogenic patients (idiopathic hyperandrogenism blue, ovulatory PCOS fuchsia, and PCOS red). Modified from Carmina et al. (6)). **P<.01 vs. normal controls, patients with idiopathic hyperandrogenism, and patients with ovulatory PCOS. Carmina. Main hyperandrogenic disorders. Fertil Steril 2006. Fertility and Sterility 2006 85, 1582-1585DOI: (10.1016/j.fertnstert.2006.02.069) Copyright © 2006 American Society for Reproductive Medicine Terms and Conditions