Molly Bridges Bouldin, MD, Holly E. Clowers-Webb, MD, Jaime L

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Naproxen-Associated Linear IgA Bullous Dermatosis: Case Report and Review Molly Bridges Bouldin, MD, Holly E. Clowers-Webb, MD, Jaime L. Davis, MD, Marian T. McEvoy, MD, Mark D.P. Davis, MD Mayo Clinic Proceedings Volume 75, Issue 9, Pages 967-970 (September 2000) DOI: 10.4065/75.9.967 Copyright © 2000 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 1 Multiple large, tense, fluid-filled bullae involving the lower abdomen (left) and buttocks (right). Mayo Clinic Proceedings 2000 75, 967-970DOI: (10.4065/75.9.967) Copyright © 2000 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 2 Skin biopsy specimen (left) shows subepidermal bulla with neutrophils, eosinophils, and lymphocytes; neutrophilic papillitis; and a mild superficial perivascular infiltrate of neutrophils, eosinophils, and lymphocytes (hematoxylin-eosin, original magnification ×200). Direct immunofluorescence (right) from lesional skin. Linear deposition of IgA at the basement membrane zone is consistent with linear IgA bullous dermatosis (original magnification ×200). Mayo Clinic Proceedings 2000 75, 967-970DOI: (10.4065/75.9.967) Copyright © 2000 Mayo Foundation for Medical Education and Research Terms and Conditions