A Tale of Division and Polarization in the Mammalian Embryo

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Presentation transcript:

A Tale of Division and Polarization in the Mammalian Embryo Shankar Srinivas, Tristan Argeo Rodriguez Developmental Cell Volume 40, Issue 3, Pages 215-216 (February 2017) DOI: 10.1016/j.devcel.2017.01.008 Copyright © 2017 Terms and Conditions

Figure 1 Importance of the Apical Domain for Inner Cell Mass versus Trophectoderm Lineage Segregation (A) Diagrammatic representation of the developmental stages of a mini-blastocyst. (B) Roles of the apical domain in TE specification. The apical domain is required to regulate the Hippo pathway in order to drive asymmetric cell division and to ensure that polarized cells remain on the outside of the embryo. Developmental Cell 2017 40, 215-216DOI: (10.1016/j.devcel.2017.01.008) Copyright © 2017 Terms and Conditions