Prospective randomized comparison of CarboMedics and St

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Prospective randomized comparison of CarboMedics and St Prospective randomized comparison of CarboMedics and St. Jude Medical bileaflet mechanical heart valve prostheses: Ten-year follow-up Alan J. Bryan, MD, FRCS, Chris A. Rogers, BSc, PhD, Kate Bayliss, BSc, Jan Wild, Gianni D. Angelini, MD, MCh, FRCS The Journal of Thoracic and Cardiovascular Surgery Volume 133, Issue 3, Pages 614-622.e2 (March 2007) DOI: 10.1016/j.jtcvs.2006.08.075 Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Kaplan–Meier plots: overall patient survival (A), freedom from valve-related death (B), and patient survival for AVR only (C) and MVR only (D). CM, CarboMedics; SJM, St. Jude Medical; CI, confidence interval; AVR, aortic valve replacement; MVR, mitral valve replacement. The Journal of Thoracic and Cardiovascular Surgery 2007 133, 614-622.e2DOI: (10.1016/j.jtcvs.2006.08.075) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Kaplan–Meier plots: freedom from thromboembolism for all study patients (A), for AVR only (B), for MVR only (C), and by position of valve replacement (D). Abbreviation definitions as in Figure 1. The Journal of Thoracic and Cardiovascular Surgery 2007 133, 614-622.e2DOI: (10.1016/j.jtcvs.2006.08.075) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Kaplan-Meier plots: bleeding event-free survival for all study patients (A), for AVR only (B), for MVR only (C), and by position of valve replacement (D). Abbreviation definitions as in Figure 1. The Journal of Thoracic and Cardiovascular Surgery 2007 133, 614-622.e2DOI: (10.1016/j.jtcvs.2006.08.075) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Complication-free survival by study group (A) and position of valve replacement (B). Abbreviation definitions as in Figure 1. The Journal of Thoracic and Cardiovascular Surgery 2007 133, 614-622.e2DOI: (10.1016/j.jtcvs.2006.08.075) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 5 NYHA class by year of follow-up. NYHA, New York Heart Association. The Journal of Thoracic and Cardiovascular Surgery 2007 133, 614-622.e2DOI: (10.1016/j.jtcvs.2006.08.075) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure E1 Flow chart showing study recruitment and randomization. CM, CarboMedics; SJM, St. Jude Medical. The Journal of Thoracic and Cardiovascular Surgery 2007 133, 614-622.e2DOI: (10.1016/j.jtcvs.2006.08.075) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure E2 Anticoagulation control. INR, international normalized ratio; SJM, St. Jude Medical; CM, CarboMedics; AVR, aortic valve replacement; MVR, mitral valve replacement; DVR, double valve replacement. The Journal of Thoracic and Cardiovascular Surgery 2007 133, 614-622.e2DOI: (10.1016/j.jtcvs.2006.08.075) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions