Prospective evaluation of the relationship between C-reactive protein, D-dimer and progression of peripheral arterial disease Scott E. Musicant, MD,

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Presentation transcript:

Prospective evaluation of the relationship between C-reactive protein, D-dimer and progression of peripheral arterial disease Scott E. Musicant, MD, Lloyd M. Taylor, MD, Dawn Peters, PhD, Robert A. Schuff, MS, Rakhee Urankar, MD, Gregory J. Landry, MD, Gregory L. Moneta, MD Journal of Vascular Surgery Volume 43, Issue 4, Pages 772-780 (April 2006) DOI: 10.1016/j.jvs.2005.12.051 Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 1 Overall percentage of subjects meeting primary and secondary end points. ABI, ankle-brachial index; MI, myocardial infarction. Journal of Vascular Surgery 2006 43, 772-780DOI: (10.1016/j.jvs.2005.12.051) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 2 Life-table survival curves for death from cardiovascular disease and death from any cause for highest vs lowest tertiles of D-dimer levels. Journal of Vascular Surgery 2006 43, 772-780DOI: (10.1016/j.jvs.2005.12.051) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 3 Life-table survival curves for the primary composite end point (ankle-brachial index decrease, carotid duplex progression, vascular death, myocardial infarction, stroke, amputation) for highest vs lowest tertiles of D-dimer and C-reactive protein (CRP) levels. Journal of Vascular Surgery 2006 43, 772-780DOI: (10.1016/j.jvs.2005.12.051) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 4 Hazard ratios for multivariate Cox proportional hazards analysis of myocardial infarction (MI). CI, Confidence interval; CRP, C-reactive protein. Journal of Vascular Surgery 2006 43, 772-780DOI: (10.1016/j.jvs.2005.12.051) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 5 Hazard ratios for multivariate Cox proportional hazards analysis of death from cardiovascular disease. CI, Confidence interval; CRP, C-reactive protein. Journal of Vascular Surgery 2006 43, 772-780DOI: (10.1016/j.jvs.2005.12.051) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 6 Hazard ratios for multivariate Cox proportional hazards analysis of death from any cause. CI, Confidence interval; CRP, C-reactive protein. Journal of Vascular Surgery 2006 43, 772-780DOI: (10.1016/j.jvs.2005.12.051) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 7 Hazard ratios for multivariate Cox proportional hazards analysis of the primary composite end point (ankle-brachial index decrease, carotid duplex progression, vascular death, myocardial infarction, stroke, amputation). CI, Confidence interval; CRP, C-reactive protein. Journal of Vascular Surgery 2006 43, 772-780DOI: (10.1016/j.jvs.2005.12.051) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions