Prolonged Survival in a Case of Chemotherapy-Sensitive Gastric Cancer That Produced Alpha-Fetoprotein and Protein Induced by Vitamin K Antagonist-II Case.

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Prolonged Survival in a Case of Chemotherapy-Sensitive Gastric Cancer That Produced Alpha-Fetoprotein and Protein Induced by Vitamin K Antagonist-II Case Rep Gastroenterol 2015;9:113-119 - DOI:10.1159/000382072 Fig. 1. CT on admission and 25 months after chemotherapy. Enhanced CT on admission revealed ring enhancement around the periphery of the tumors and heterogeneous enhancement within the tumors (a). CT also revealed multiple hepatic tumors with heterogeneous enhancement, and a swollen lymph node surrounding the lesser curve of the stomach (b, arrowhead). Thickening of the stomach wall was indicative of a gastric tumor that was thought to have invaded the muscularis propria (c, arrowheads). MRI on admission showed enhancement at the periphery of the tumors and heterogeneous enhancement within the tumors in the arterial phase (d), but there was no enhancement during the delayed phase (e). CT finding 25 months after chemotherapy showed a remarkable reduction in the size of the metastatic liver tumors without enhancement (f). © 2015 S. Karger AG, Basel - CC BY-NC 3.0

Prolonged Survival in a Case of Chemotherapy-Sensitive Gastric Cancer That Produced Alpha-Fetoprotein and Protein Induced by Vitamin K Antagonist-II Case Rep Gastroenterol 2015;9:113-119 - DOI:10.1159/000382072 Fig. 2. Endoscopic findings before chemotherapy and 25 months after chemotherapy. EGD before chemotherapy revealed a Bormann type 3 advanced tumor about 30 mm in diameter in the lower part of the stomach (a). Closer view of the gastric tumor (b). EGD performed 8 months after chemotherapy showed a remarkable reduction in the size of the tumor, which had the appearance of an excavated lesion with marginal protrusion (c). EGD performed 25 months after chemotherapy revealed an even greater reduction in the size of the tumor, which had the appearance of an extremely small elevated lesion with a scar (d). © 2015 S. Karger AG, Basel - CC BY-NC 3.0

Prolonged Survival in a Case of Chemotherapy-Sensitive Gastric Cancer That Produced Alpha-Fetoprotein and Protein Induced by Vitamin K Antagonist-II Case Rep Gastroenterol 2015;9:113-119 - DOI:10.1159/000382072 Fig. 3. Hematoxylin and eosin (HE) staining and immunohistochemical findings of the gastric tumor biopsy specimen. HE staining revealed that the tumor was a poorly differentiated adenocarcinoma (a). Immunohistochemical evaluation of a tumor biopsy specimen revealed that the tumor cells were positive for AFP (b), PIVKA-II (c), and HER2 (d). Original magnification ×400 (a-d). © 2015 S. Karger AG, Basel - CC BY-NC 3.0