Inverse lichenoid drug eruption associated with nivolumab

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Inverse lichenoid drug eruption associated with nivolumab Lauren M. Guggina, MD, Daniel A. Yanes, BS, Jennifer N. Choi, MD  JAAD Case Reports  Volume 3, Issue 1, Pages 7-9 (January 2017) DOI: 10.1016/j.jdcr.2016.11.002 Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 A, Erythematous-to-violaceous confluent patches with peripheral desquamative scale spanning the inguinal creases, labia majora, and clitoris. B, Erythematous-to-violaceous scaling patches involving the perineum and sparing the perianal area. JAAD Case Reports 2017 3, 7-9DOI: (10.1016/j.jdcr.2016.11.002) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Pathology findings show a lichenoid infiltrate, with acanthosis, hypergranulosis, and a superficial bandlike lymphohistiocytic infiltrate with scattered eosinophils and necrotic keratinocytes. JAAD Case Reports 2017 3, 7-9DOI: (10.1016/j.jdcr.2016.11.002) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions