Nariman Sepehrvand, and Justin A. Ezekowitz JCHF 2016;4:

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Nariman Sepehrvand, and Justin A. Ezekowitz JCHF 2016;4:783-790 Schematic Illustration of the Potential Mechanism of Effect of Hyperoxygenation on Patients With Cardiac Disease Solid lines represent the availability of strong evidence supporting the proposed process. Dotted lines represent the availability of some but not strong supporting evidence. BP = blood pressure; CaO2 = arterial oxygen content; CO = cardiac output; DO2 = tissue oxygen delivery; ET = endothelin; HR = heart rate; IRI = ischemia/reperfusion injury; KATP = adenosine triphosphate–dependent potassium channels; NO = nitric oxide; PaCO2 = partial arterial carbon dioxide pressure; PaO2 = partial arterial oxygen pressure; PGI2 = prostacyclin; ROS = reactive oxygen species; RR = respiratory rate. Nariman Sepehrvand, and Justin A. Ezekowitz JCHF 2016;4:783-790 2016 American College of Cardiology Foundation