Autologous Platelet-Rich Plasma Reduces Transfusions During Ascending Aortic Arch Repair: A Prospective, Randomized, Controlled Trial  Shao Feng Zhou,

Slides:



Advertisements
Similar presentations
Impact of Autologous Platelet Rich Plasma Transfusion On Clinical Outcomes in Descending Thoracic Abdominal Aortic Aneurysm Repair Cardiothoracic and Vascular.
Advertisements

Impact of Autologous Platelet Rich Plasma Transfusion On Clinical Outcomes In Ascending Aortic Surgery With Deep Hypothermic Circulatory Arrest Cardiothoracic.
Daniel Bolliger, MD, Gautam Sreeram, MD, Alexander Duncan, MD, Ross J
Paul E. Achouh, MD, Anthony L. Estrera, MD, Charles C
Bloodless Surgery of Acute Type A Aortic Dissection in a Jehovah’s Witness Patient  Miralem Pasic, MD, PhD, Wolfgang Ruisz, MD, Andreas Koster, MD, PhD,
Major Bleeding, Transfusions, and Anemia: The Deadly Triad of Cardiac Surgery  Marco Ranucci, MD, FESC, Ekaterina Baryshnikova, BD, Serenella Castelvecchio,
Analysis of motor and somatosensory evoked potentials during thoracic and thoracoabdominal aortic aneurysm repair  Kourosh Keyhani, DO, Charles C. Miller,
Rana O. Afifi, MD, Harleen K. Sandhu, MD, MPH, Amy. E
Rana O. Afifi, MD, Harith H. Mushtaq, MD, Harleen K
Gaetano Paone, MD, MHSA, Robert Brewer, MD, MHSA, Donald S
Postoperative risk factors for delayed neurologic deficit after thoracic and thoracoabdominal aortic aneurysm repair: A case-control study  Ali Azizzadeh,
Fibrinogen Levels After Cardiac Surgical Procedures: Association With Postoperative Bleeding, Trigger Values, and Target Values  Marco Ranucci, MD, Valeria.
Daniel Bolliger, MD, Gautam Sreeram, MD, Alexander Duncan, MD, Ross J
Anthony L. Estrera, MD, Zsolt Garami, MD, Charles C
Robert J Cerfolio, MD, Cyndi Bass, MSN, Charles R Katholi, PhD 
Mina L. Boutrous, MD, Rana O. Afifi, MD, Hazim J. Safi, MD, Anthony L
Amr Mohammad Allama, MD  The Annals of Thoracic Surgery 
Platelet Transfusion in Cardiac Surgery Does Not Confer Increased Risk for Adverse Morbid Outcomes  Tory McGrath, MD, Colleen Gorman Koch, MD, MS, Meng.
Total Arch Replacement Under Normothermic Beating Heart Surgery
Intraoperative Hemoglobin Levels and Transfusion Independently Predict Stroke After Cardiac Operations  Zainab S. Bahrainwala, BS, Maura A. Grega, RN,
Anthony L. Estrera, MD, Charles C
Loretta Erhunmwunsee, MD, Brian C
Denton A. Cooley, August 22, 1920, to November 18, 2016
Analysis of motor and somatosensory evoked potentials during thoracic and thoracoabdominal aortic aneurysm repair  Kourosh Keyhani, DO, Charles C. Miller,
Emergency Coronary Artery Bypass Grafting Can Be Performed Safely Without Cardiopulmonary Bypass in Selected Patients  Faraz Kerendi, MD, John D. Puskas,
Development of New Acute Dissection in the Ascending Aorta After Type B Dissection: Intramural Hematoma Is Not Benign  Samuel S. Leake, BS, Harleen K.
Transfusion Increases the Risk for Vasoplegia After Cardiac Operations
Risk Modeling to Optimize Patient Selection for Management of the Descending Thoracic Aortic Aneurysm  Akiko Tanaka, MD, PhD, Harleen K. Sandhu, MD, MPH,
The hybrid elephant trunk procedure: A single-stage repair of an ascending, arch, and descending thoracic aortic aneurysm  Ali Azizzadeh, MD, Anthony.
Susanne Lison, MD, Michael Spannagl, MD, PhD, Wulf Dietrich, MD, PhD 
John Alfred Carr, MD, Joseph J. Amato, MD, Robert S.D. Higgins, MD 
Anthony L. Estrera, MD, Roy Sheinbaum, MD, Charles C
Tomoaki Murakami, MD, PhD, Atsuhito Takeda, MD, PhD 
James D. St. Louis, MD  The Annals of Thoracic Surgery 
Mariano E. Brizzio, MD, Alex Zapolanski, MD, Richard E
Who Do You Say You Are? The Annals of Thoracic Surgery
Paul E. Achouh, MD, Anthony L. Estrera, MD, Charles C
Seth D. Goldstein, MD, Stephen C. Yang, MD 
Impact of Blood Product Transfusion on Short and Long-Term Survival After Cardiac Surgery: More Evidence  Balu Bhaskar, MD, FCICM, Joel Dulhunty, PhD,
Risks and Predictors of Blood Transfusion in Pediatric Patients Undergoing Open Heart Operations  Andrea Székely, MD, PhD, Zsuzsanna Cserép, MD, Erzsébet.
Type A Aortic Dissection With Cold Agglutinin Disease
Wrapping Procedure for Stanford Type A Acute Aortic Dissection: Is There an Indication for Surgery Without a Cardiopulmonary Bypass?  Stéphane Lopez,
Percutaneous Transcatheter Closure of the Aortic Valve
Gerald G.R. Sng, Cameron D. Wright, MD  The Annals of Thoracic Surgery 
Benjamin C. Sun, MD, Timothy A. Dickinson, CCP, Eric A
Bradford B. Smith, MD, Matthew A
Red Blood Cell Transfusion Is Associated With Troponin Release After Elective Off- Pump Coronary Artery Bypass Surgery  Fausto Biancari, MD, PhD, Eeva-Maija.
Completely Thrombosed Tricuspid Pouch Mimicking a Cardiac Tumor
Anthony L. Estrera, MD, Charles C
Stany Sandrio, MD, Ariawan Purbojo, MD, Robert A
Paul Urbanski, MD, PhD  The Annals of Thoracic Surgery 
Pallav J. Shah, MD, Anthony L. Estrera, MD, Charles C
Optimization of Aortic Arch Replacement: Two-Stage Approach
Randomized Controlled Trial of Pericardial Blood Processing With a Cell-Saving Device on Neurologic Markers in Elderly Patients Undergoing Coronary Artery.
Anthony L. Estrera, MD, David C
Postoperative Cognitive Dysfunction and Aortic Atheroma
Experience With Bovine Pericardium for the Reconstruction of the Aortic Arch in Patients Undergoing a Norwood Procedure  Victor O. Morell, MD, Peter A.
Dumbor L. Ngaage, MD, FRCS (C-Th), Michael E. Cowen, FRCS 
Descending Thoracic Aortic Aneurysm Repair: 12-Year Experience Using Distal Aortic Perfusion and Cerebrospinal Fluid Drainage  Anthony L. Estrera, MD,
Late Consequences of a Much Earlier Decision
The Impact of New Technology on Cardiothoracic Surgical Practice
Self-Management of Oral Anticoagulation Therapy Improves Long-Term Survival in Patients With Mechanical Heart Valve Replacement  Heinrich Koertke, MD,
Bloodless Surgery of Acute Type A Aortic Dissection in a Jehovah’s Witness Patient  Miralem Pasic, MD, PhD, Wolfgang Ruisz, MD, Andreas Koster, MD, PhD,
Slide Tracheoplasty in Infants and Children: Risk Factors for Prolonged Postoperative Ventilatory Support  Peter B. Manning, MD, Michael J. Rutter, MD,
Domenico Galetta, MD, PhD, Lorenzo Spaggiari, MD, PhD 
Staged repair of extensive aortic aneurysms
Karl A. Bocchieri, BS, CCP, S. Jacob Scheinerman, MD, L
Safety of low hematocrits during cardiopulmonary bypass
Harvey Edward Garrett, MD, Bradley A. Wolf, MD 
Wrapping of the Ascending Aorta in Acute Type A Retrograde Aortic Dissection  Ramzi Ramadan, MD, Alexandre Azmoun, MD, Nawwar Al-Attar, FRCS, PhD, Remi.
Presentation transcript:

Autologous Platelet-Rich Plasma Reduces Transfusions During Ascending Aortic Arch Repair: A Prospective, Randomized, Controlled Trial  Shao Feng Zhou, MD, Anthony L. Estrera, MD, Paul Loubser, MD, Craig Ignacio, MD, Sreelatha Panthayi, MD, Charles Miller, PhD, Roy Sheinbaum, MD, Hazim J. Safi, MD  The Annals of Thoracic Surgery  Volume 99, Issue 4, Pages 1282-1290 (April 2015) DOI: 10.1016/j.athoracsur.2014.11.007 Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Whole blood is harvested from the patient and separated into the red blood cell (RBC) fraction and the autologous platelet-rich plasma (aPRP) fraction. Red blood cells may be retransfused at any time during the procedure. The aPRP fraction is reinfused after cardiopulmonary bypass is completed and anticoagulation is reversed. The Annals of Thoracic Surgery 2015 99, 1282-1290DOI: (10.1016/j.athoracsur.2014.11.007) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Perioperative hematocrit (Hct; blue, red lines and symbols) and platelet levels (green, purple lines and symbols) for the autologous platelet-rich plasma (aPRP; blue, green lines and symbols) and without aPRP (red, purple lines and symbols) groups. (Post-OP = postoperative; Pre-OP = preoperative.) The Annals of Thoracic Surgery 2015 99, 1282-1290DOI: (10.1016/j.athoracsur.2014.11.007) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Perioperative coagulation studies for the autologous platelet-rich plasma (aPRP; blue, green, light aqua lines and symbols) and without aPRP (red, purple, orange lines and symbols) groups. (INR = international normalized ratio; PT = prothrombin time; PTT = partial thromboplastin time.) The Annals of Thoracic Surgery 2015 99, 1282-1290DOI: (10.1016/j.athoracsur.2014.11.007) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions