Evolving Gene Therapy in Primary Immunodeficiency

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Evolving Gene Therapy in Primary Immunodeficiency Adrian J. Thrasher, David A. Williams  Molecular Therapy  Volume 25, Issue 5, Pages 1132-1141 (May 2017) DOI: 10.1016/j.ymthe.2017.03.018 Copyright © 2017 The American Society of Gene and Cell Therapy Terms and Conditions

Figure 1 The Development of Viral Vector Technology and Its Application to Human Gene Therapy The blue time line shows the various ups and downs of the field based on successes and setbacks. References are included in the text. Molecular Therapy 2017 25, 1132-1141DOI: (10.1016/j.ymthe.2017.03.018) Copyright © 2017 The American Society of Gene and Cell Therapy Terms and Conditions

Figure 2 A Table of Published and Ongoing Clinical Trials for Primary Immune Deficiencies The disease, mutated gene, vector platform, use of conditioning, and year are included. Molecular Therapy 2017 25, 1132-1141DOI: (10.1016/j.ymthe.2017.03.018) Copyright © 2017 The American Society of Gene and Cell Therapy Terms and Conditions