Evaluation of a low-dose oral contraceptive pill for primary dysmenorrhea: a placebo- controlled, double-blind, randomized trial Tasuku Harada, M.D.,

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Presentation transcript:

Evaluation of a low-dose oral contraceptive pill for primary dysmenorrhea: a placebo- controlled, double-blind, randomized trial Tasuku Harada, M.D., Mikio Momoeda, M.D., Naoki Terakawa, M.D., Yuji Taketani, M.D., Hiroshi Hoshiai, M.D. Fertility and Sterility Volume 95, Issue 6, Pages 1928-1931 (May 2011) DOI: 10.1016/j.fertnstert.2011.02.045 Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Profile of the randomized controlled trial. FAS = full analysis set. aPatient choice. bReasons for no available data: shortage of day received (n = 3); 2–4 days intake (n = 2). cReason for no available data (n =1). dReason for no available data (n = 1). Fertility and Sterility 2011 95, 1928-1931DOI: (10.1016/j.fertnstert.2011.02.045) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Changes in mean dysmenorrhea score and visual analog scale (VAS) during the trial. The mean (±SD) of total dysmenorrhea score, pain score, drug score and VAS in the IKH-01 and placebo groups are shown from the pretreatment cycle to cycle 5. ∗∗ P<0.01 IKH-01 vs placebo. Fertility and Sterility 2011 95, 1928-1931DOI: (10.1016/j.fertnstert.2011.02.045) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions