Significance of Programmed Cell Death-Ligand 1 Expression and its Association with Survival in Patients with Small Cell Lung Cancer Hidenobu Ishii, MD,

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Presentation transcript:

Significance of Programmed Cell Death-Ligand 1 Expression and its Association with Survival in Patients with Small Cell Lung Cancer Hidenobu Ishii, MD, Koichi Azuma, MD, PhD, Akihiko Kawahara, PhD, Kazuhiko Yamada, MD, PhD, Yohei Imamura, MD, Takaaki Tokito, MD, PhD, Takashi Kinoshita, MD, PhD, Masayoshi Kage, MD, PhD, Tomoaki Hoshino, MD, PhD Journal of Thoracic Oncology Volume 10, Issue 3, Pages 426-430 (March 2015) DOI: 10.1097/JTO.0000000000000414 Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Positive PD-L1 immunohistochemical staining pattern (A) and negative immunohistochemical staining pattern (B). PD-L1, programmed cell death-ligand 1. Journal of Thoracic Oncology 2015 10, 426-430DOI: (10.1097/JTO.0000000000000414) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Kaplan–Meier overall survival curves for SCLC patients with positive and negative expression of PD-L1. SCLC, small-cell lung cancer; PD-L1, programmed cell death-ligand 1. Journal of Thoracic Oncology 2015 10, 426-430DOI: (10.1097/JTO.0000000000000414) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Kaplan–Meier curves for OS (A) and PFS (B) of ED-SCLC patients with high or low expression of PD-L1. Kaplan–Meier curves for OS (C) and PFS (D) of LD-SCLC patients with positive or negative expression of PD-L1. OS, overall survival; PFS, progression-free survival; ED, extensive disease; SCLC, small-cell lung cancer; PD-L1, programmed cell death-ligand 1; LD, limited disease. Journal of Thoracic Oncology 2015 10, 426-430DOI: (10.1097/JTO.0000000000000414) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions