Eamonn M.M. Quigley Clinical Gastroenterology and Hepatology

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Presentation transcript:

A 51-Year-Old With Irritable Bowel Syndrome: Test or Treat for Bacterial Overgrowth? Eamonn M.M. Quigley Clinical Gastroenterology and Hepatology Volume 5, Issue 10, Pages 1140-1143 (October 2007) DOI: 10.1016/j.cgh.2007.07.019 Copyright © 2007 AGA Institute Terms and Conditions

Figure 1 Interactions between the enteric flora and luminal contents in the pathogenesis of symptoms in IBS. Disturbances in the enteric flora (microbiota) in the form of SIBO or qualitative changes in the colonic flora interact with luminal carbohydrates (aggravated in conditions of carbohydrate malabsorption or maldigestion) to lead to increased bacterial fermentation and gas production. This in turn affects gut physiology by delaying gastric emptying and small-bowel transit. Clinical Gastroenterology and Hepatology 2007 5, 1140-1143DOI: (10.1016/j.cgh.2007.07.019) Copyright © 2007 AGA Institute Terms and Conditions