Hypertonic Saline Dextran Improves Outcome After Hypothermic Circulatory Arrest: A Study in a Surviving Porcine Model Timo Kaakinen, MD, Hanna Alaoja,

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Presentation transcript:

Hypertonic Saline Dextran Improves Outcome After Hypothermic Circulatory Arrest: A Study in a Surviving Porcine Model Timo Kaakinen, MD, Hanna Alaoja, MS, Janne Heikkinen, MD, Sebastian Dahlbacka, MS, Päivi Laurila, MD, PhD, Kai Kiviluoma, MD, PhD, Timo Salomäki, MD, PhD, Hannu Tuominen, MD, PhD, Pasi Ohtonen, MS, Fausto Biancari, MD, PhD, Tatu Juvonen, MD, PhD The Annals of Thoracic Surgery Volume 81, Issue 1, Pages 183-190 (January 2006) DOI: 10.1016/j.athoracsur.2005.07.017 Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Postoperative behavioral scores in the study groups. * p = 0.03 vs control group (second postoperative day). Horizontal lines indicate median values. The cumulative behavioral score was also counted, it being the sum of all daily scores, representing overall recovery. The Annals of Thoracic Surgery 2006 81, 183-190DOI: (10.1016/j.athoracsur.2005.07.017) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Venous sodium levels during the experimental period. Values are shown as medians along with 25th and 75th percentiles. (inf = infusion of either hypersonic saline dextra (HSD) or 0.9% NaCl; ■ = HSD; ○ = Control.) The Annals of Thoracic Surgery 2006 81, 183-190DOI: (10.1016/j.athoracsur.2005.07.017) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Intracranial measurements. Values are shown as medians and 25th and 75th percentiles. (inf = infusion of either hypersonic saline dextra (HSD) or 0.9% NaCl; * p < 0.05 between the study groups; ** p < 0.01 between the study groups; ■ = HSD; ○ = Control.) The Annals of Thoracic Surgery 2006 81, 183-190DOI: (10.1016/j.athoracsur.2005.07.017) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions