POPsicle for Fever! Cooling Down the Inflammasome

Slides:



Advertisements
Similar presentations
How T Cells Earn the Follicular Rite of Passage Carola G. Vinuesa, Jason G. Cyster Immunity Volume 35, Issue 5, Pages (November 2011) DOI: /j.immuni
Advertisements

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.
What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell
Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni
Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet
The Transcription Factor Foxo1 Controls Central-Memory CD8+ T Cell Responses to Infection Myoungjoo V. Kim, Weiming Ouyang, Will Liao, Michael Q. Zhang,
Lung Natural Helper Cells Are a Critical Source of Th2 Cell-Type Cytokines in Protease Allergen-Induced Airway Inflammation Timotheus Y.F. Halim, Ramona.
Human Epidermal Langerhans Cells Maintain Immune Homeostasis in Skin by Activating Skin Resident Regulatory T Cells Julien Seneschal, Rachael A. Clark,
Lung Airway-Surveilling CXCR3hi Memory CD8+ T Cells Are Critical for Protection against Influenza A Virus Bram Slütter, Lecia L. Pewe, Susan M. Kaech,
Mechanisms of Age-Related Macular Degeneration Jayakrishna Ambati, Benjamin J. Fowler Neuron Volume 75, Issue 1, Pages (July 2012) DOI: /j.neuron
Septic Shock: On the Importance of Being Tolerant
“Toll”-erance in the Skin
Approaching the Asymptote: 20 Years Later
Volume 31, Issue 2, Pages (August 2009)
Amit Awasthi, Vijay K. Kuchroo  Immunity 
CD5: A New Partner for IL-6
Sky W. Brubaker, Denise M. Monack  Immunity 
Cryopyrin: In from the Cold
“Sweet Talk”: Closing in on C Type Lectin Signaling
Immobile BCRs: The Safety on the Signal Trigger
Toll Signaling in Flies and Mammals: Two Sorts of MyD88
The Birds, the Bees, and Innate Immunity
Volume 29, Issue 5, Pages (November 2008)
Chronic Infections Capture Little Attention of the Masses
JAK's SOCS: A Mechanism of Inhibition
Checks and Balances: IL-23 in the Intestine
Juan Rivera, Lino Tessarollo  Immunity 
Warfare between Host Immunity and Bacterial Weapons
Unraveling the Pros and Cons of Interferon-γ Gene Regulation
Is Predisposition to NAFLD and Obesity Communicable?
PU.1 Takes Control of the Dendritic Cell Lineage
Sweet NETs, Bitter Wounds
God's Gift to Women: The Human Papillomavirus Vaccine
Copyright © 2012, Elsevier Inc. All rights Reserved.
Chronic Infections Capture Little Attention of the Masses
E Proteins Enforce Security Checkpoints in the Thymus
Sky W. Brubaker, Denise M. Monack  Immunity 
Copyright © 2013 Elsevier Inc. All rights reserved.
Copyright © 2012, Elsevier Inc. All rights Reserved.
Dangerous Liaisons: Mitochondrial DNA Meets the NLRP3 Inflammasome
Copyright © 2012, Elsevier Inc. All rights Reserved.
Copyright © 2013 Elsevier Inc. All rights reserved.
Immune and Nervous Systems: More Than Just a Superficial Similarity?
From Vanilla to 28 Flavors: Multiple Varieties of T Regulatory Cells
ILC Lineage Specification: To Be or Not 11b, That Is the Question
Poxviruses Aren't StuPYD
A Prescription for Human Immunology
HIV and HLA Class I: An Evolving Relationship
Poxviruses Aren't StuPYD
Volume 30, Issue 2, Pages (February 2009)
GR Extinguishes Inflamed Chromatin, and NF-κB Evacuates
Modeling Functionality with Use Cases
Copyright © 2012, Elsevier Inc. All rights Reserved.
Inflammasome: Putting the Pieces Together
Eystein S. Husebye, Mark S. Anderson  Immunity 
MicroRNA-155 Function in B Cells
Eystein S. Husebye, Mark S. Anderson  Immunity 
Copyright © 2012, Elsevier Inc. All rights Reserved.
Copyright © 2013 Elsevier Inc. All rights reserved.
Copyright © 2013 Elsevier Inc. All rights reserved.
Releasing the Brakes on Cancer Immunotherapy
Licensing PPARγ to Work in Macrophages
Copyright © 2012, Elsevier Inc. All rights Reserved.
Regulatory T Cells GATA Have It
t Testing the Immune System
David Hubel and Torsten Wiesel
Notch 1 Keeps Pro-T cells on Track
Marking Emerging β- and γδ-Selected T Cells
IL-9 by INFERence Immunity
Of Human DC Migrants and Residents
Presentation transcript:

POPsicle for Fever! Cooling Down the Inflammasome Kenichi Shimada, Timothy R. Crother, Moshe Arditi  Immunity  Volume 43, Issue 2, Pages 213-215 (August 2015) DOI: 10.1016/j.immuni.2015.08.004 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Mechanisms of Inflammasome Inhibition Left: POP1 binds to the PYD of ASC and prevents PYD-PYD interactions between ASC and NLRP3. Right: multiple inflammasome inhibitory mechanisms are shown, including POP1. Immunity 2015 43, 213-215DOI: (10.1016/j.immuni.2015.08.004) Copyright © 2015 Elsevier Inc. Terms and Conditions

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2025 SlidePlayer.com. Inc. All rights reserved.