Acute mixed lineage leukemia in children: the experience of St Jude Children's Research Hospital by Jeffrey E. Rubnitz, Mihaela Onciu, Stanley Pounds,

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Presentation transcript:

Acute mixed lineage leukemia in children: the experience of St Jude Children's Research Hospital by Jeffrey E. Rubnitz, Mihaela Onciu, Stanley Pounds, Sheila Shurtleff, Xueyuan Cao, Susana C. Raimondi, Frederick G. Behm, Dario Campana, Bassem I. Razzouk, Raul C. Ribeiro, James R. Downing, and Ching-Hon Pui Blood Volume 113(21):5083-5089 May 21, 2009 ©2009 by American Society of Hematology

Principal components plot based on 284 lineage-distinguishing probe sets. Principal components plot based on 284 lineage-distinguishing probe sets. Purple spheres represent cases of T-ALL; blue spheres, B-progenitor ALL; red spheres, AML; and green spheres, mixed lineage leukemia. Jeffrey E. Rubnitz et al. Blood 2009;113:5083-5089 ©2009 by American Society of Hematology

Kaplan-Meier plot of overall survival for patients with ALL, AML, T/myeloid, and B/myeloid biphenotypic leukemia. Kaplan-Meier plot of overall survival for patients with ALL, AML, T/myeloid, and B/myeloid biphenotypic leukemia. Five-year survival estimates are shown. Jeffrey E. Rubnitz et al. Blood 2009;113:5083-5089 ©2009 by American Society of Hematology