Lung Cancer Staging: A Case for a New T Definition

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Lung Cancer Staging: A Case for a New T Definition Major Charles R. Mulligan, MC, USA, Amir D. Meram, MD, Courtney D. Proctor, Hongyu Wu, MD, Kangmin Zhu, PhD, Aizen J. Marrogi, LTC, MC, USA The Annals of Thoracic Surgery Volume 82, Issue 1, Pages 220-226 (July 2006) DOI: 10.1016/j.athoracsur.2006.02.032 Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 The graph depicts the dispersion of tumor size and pathologic stage. Note the increasing incidence of advanced stage cancer with increasing size. The Annals of Thoracic Surgery 2006 82, 220-226DOI: (10.1016/j.athoracsur.2006.02.032) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Tumor size and relative risk compared with overall cure rates for each size tumor. Note the transitions occurring at 2.0 cm and 4.0 cm for both curves. The Annals of Thoracic Surgery 2006 82, 220-226DOI: (10.1016/j.athoracsur.2006.02.032) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Stage groupings and their changes based upon new T definition. The arrows reflect the stage migration of the new T definition and the number which changed stage. The Annals of Thoracic Surgery 2006 82, 220-226DOI: (10.1016/j.athoracsur.2006.02.032) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Kaplan–Meier survival curves comparing current and new staging systems, showing the difference in stage I cancers (A); stage II cancers (B); stage III cancers (C); and stage IV cancer (D). The Annals of Thoracic Surgery 2006 82, 220-226DOI: (10.1016/j.athoracsur.2006.02.032) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions