Impact of Intravenous Magnesium on Post-Cardiothoracic Surgery Atrial Fibrillation and Length of Hospital Stay: A Meta-Analysis Nickole N. Henyan, PharmD,

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Presentation transcript:

Impact of Intravenous Magnesium on Post-Cardiothoracic Surgery Atrial Fibrillation and Length of Hospital Stay: A Meta-Analysis Nickole N. Henyan, PharmD, Effie L. Gillespie, PharmD, C. Michael White, PharmD, Jeffrey Kluger, MD, Craig I. Coleman, PharmD The Annals of Thoracic Surgery Volume 80, Issue 6, Pages 2402-2406 (December 2005) DOI: 10.1016/j.athoracsur.2005.03.036 Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Magnesium’s effect on postoperative atrial fibrillation (POAF). (CI = confidence interval; OR = odds ratio.) The Annals of Thoracic Surgery 2005 80, 2402-2406DOI: (10.1016/j.athoracsur.2005.03.036) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Magnesium’s dose on postoperative atrial fibrillation (low dose). (CI = confidence interval; OR = odds ratio.) The Annals of Thoracic Surgery 2005 80, 2402-2406DOI: (10.1016/j.athoracsur.2005.03.036) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Magnesium’s dose on postoperative atrial fibrillation (moderate-high dose). (CI = confidence interval; OR = odds ratio.) The Annals of Thoracic Surgery 2005 80, 2402-2406DOI: (10.1016/j.athoracsur.2005.03.036) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Time of initiation of prophylaxis (intraopertive and postoperative initiation). (CI = confidence interval; OR = odds ratio; POAF = postoperative atrial fibrillation.) The Annals of Thoracic Surgery 2005 80, 2402-2406DOI: (10.1016/j.athoracsur.2005.03.036) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Time of initiation of prophylaxis (preoperative initiation). (CI = confidence interval; OR = odds ratio; POAF = postoperative atrial fibrillation.) The Annals of Thoracic Surgery 2005 80, 2402-2406DOI: (10.1016/j.athoracsur.2005.03.036) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 Magnesium’s effect on length of stay (LOS). (CI = confidence interval; SD = standard deviation; WMD = weighted mean difference.) The Annals of Thoracic Surgery 2005 80, 2402-2406DOI: (10.1016/j.athoracsur.2005.03.036) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions