Evaluation of a novel closed-loop total intravenous anaesthesia drug delivery system: a randomized controlled trial T.M. Hemmerling, E. Arbeid, M. Wehbe,

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Presentation transcript:

Evaluation of a novel closed-loop total intravenous anaesthesia drug delivery system: a randomized controlled trial T.M. Hemmerling, E. Arbeid, M. Wehbe, S. Cyr, R. Taddei, C. Zaouter British Journal of Anaesthesia Volume 110, Issue 6, Pages 1031-1039 (June 2013) DOI: 10.1093/bja/aet001 Copyright © 2013 The Author(s) Terms and Conditions

Fig 1 Flowchart of the trial. British Journal of Anaesthesia 2013 110, 1031-1039DOI: (10.1093/bja/aet001) Copyright © 2013 The Author(s) Terms and Conditions

Fig 2 McSleepy user's interface for set up. Columns from left to right: input of patient data; input of anaesthesia and surgery-relevant data; start buttons for anaesthetic drugs including choice of two different neuromuscular blocking drugs; start button for induction of anaesthesia. British Journal of Anaesthesia 2013 110, 1031-1039DOI: (10.1093/bja/aet001) Copyright © 2013 The Author(s) Terms and Conditions

Fig 3 Flow chart showing the induction phase of the McSleepy group. British Journal of Anaesthesia 2013 110, 1031-1039DOI: (10.1093/bja/aet001) Copyright © 2013 The Author(s) Terms and Conditions

Fig 4 The control of depth of hypnosis as a percentage of the time of duration of anaesthesia. The performance is defined as ‘excellent', ‘good', ‘poor', and ‘inadequate', when the BIS is ≤10%, 11–20%, 21–30%, or >30% of the target BIS value, respectively. Data are presented as n, mean (sd). #P<0.05, *P<0.0001, Mann–Whitney U-test. British Journal of Anaesthesia 2013 110, 1031-1039DOI: (10.1093/bja/aet001) Copyright © 2013 The Author(s) Terms and Conditions

Fig 5 The control of analgesia as a percentage of time of duration of anaesthesia. Data in mean (sd). The Analgoscore is a novel pain score developed from MAP and HR to monitor intraoperative nociception, which ranges from −9 to 9. ‘Excellent' represents an Analgoscore between −3 and 3; ‘Good' represents an Analgoscore ranging from −6 to −3 or from 3 to 6; ‘Insufficient' represents an Analgoscore ranging from −9 to −6 or 6 to 9; ‘Other' refers to periods where no score was determined. Data are presented as mean (sd). *P<0.05, Mann–Whitney U-test. British Journal of Anaesthesia 2013 110, 1031-1039DOI: (10.1093/bja/aet001) Copyright © 2013 The Author(s) Terms and Conditions