Representative 3-generation pedigrees for serous cancer probands suggestive of inherited cancer susceptibility. Representative 3-generation pedigrees for.

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Representative 3-generation pedigrees for serous cancer probands suggestive of inherited cancer susceptibility. Representative 3-generation pedigrees for serous cancer probands suggestive of inherited cancer susceptibility. A, Lynch syndrome–like families. B. pancreatic cancer–prone families. +++, MLH1, MSH2, and MSH6 expressed; IHC, immunohistochemical assessment for MLH1, MSH2, and MSH6 expression; MSS, tumor microsatellite stable; nd, no data/not done. Summer B. Dewdney et al. Cancer Prev Res 2012;5:435-443 ©2012 by American Association for Cancer Research