New Neurons Don’t Talk Back

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Presentation transcript:

New Neurons Don’t Talk Back Jacques I. Wadiche, Linda Overstreet-Wadiche Neuron Volume 85, Issue 1, Pages 3-5 (January 2015) DOI: 10.1016/j.neuron.2014.12.047 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Granule Cell Feedforward and Feedback Inhibitory Circuits Mature granule cells (mGCs, left) recruit interneurons (INs) that generate feedforward inhibition to CA3 and feedback inhibition to neighboring mGCs. Due to weak synaptic connections (dotted lines), immature GCs (iGCs, right) generate little feedforward and feedback inhibition. Neuron 2015 85, 3-5DOI: (10.1016/j.neuron.2014.12.047) Copyright © 2015 Elsevier Inc. Terms and Conditions