Flow patterns in externally stented saphenous vein grafts and development of intimal hyperplasia Tomer Meirson, BS, Eyal Orion, MD, MBA, Carlo Di Mario,

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Flow Patterns in Externally Stented Saphenous Vein Grafts as Related to the Development of Intimal Hyperplasia Tomer Meirson BSc, Eyal Orion MD MBA, Carlo.

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Presentation transcript:

Flow patterns in externally stented saphenous vein grafts and development of intimal hyperplasia Tomer Meirson, BS, Eyal Orion, MD, MBA, Carlo Di Mario, MD, PhD, Carolyn Webb, PhD, Niket Patel, MD, Keith M. Channon, MD, Yanai Ben Gal, MD, David P. Taggart, MD, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 150, Issue 4, Pages 871-879 (October 2015) DOI: 10.1016/j.jtcvs.2015.04.061 Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 External stent (VEST [Vascular Graft Solutions Ltd, Tel Aviv, Israel]) deployed on saphenous vein graft, grafted to the obtuse marginal artery and the right coronary artery. The Journal of Thoracic and Cardiovascular Surgery 2015 150, 871-879DOI: (10.1016/j.jtcvs.2015.04.061) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Stented and nonstented SVGs grafted to the right coronary and circumflex arteries. Although demonstrating equivalent time-averaged wall shear stress (TAWSS) values, oscillatory shear index (OSI) values differ significantly between the 2 groups. SVG, Saphenous vein graft. The Journal of Thoracic and Cardiovascular Surgery 2015 150, 871-879DOI: (10.1016/j.jtcvs.2015.04.061) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Visible velocity vortices demonstrating nonuniform flow with recirculation eddy. The Journal of Thoracic and Cardiovascular Surgery 2015 150, 871-879DOI: (10.1016/j.jtcvs.2015.04.061) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Improved lumen uniformity → improved flow pattern → reduction of intimal hyperplasia. The Journal of Thoracic and Cardiovascular Surgery 2015 150, 871-879DOI: (10.1016/j.jtcvs.2015.04.061) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions