Taking Centrioles to the Elimination Round

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Presentation transcript:

Taking Centrioles to the Elimination Round Todd A. Schoborg, Nasser M. Rusan Developmental Cell Volume 38, Issue 1, Pages 10-12 (July 2016) DOI: 10.1016/j.devcel.2016.06.027 Copyright © 2016 Terms and Conditions

Figure 1 Mechanism of Centriole Elimination in Centrosomal and Acentrosomal Meiosis In starfish, centriole elimination (CE) occurs during centrosomal meiosis via two mechanisms: polar body (PB) extrusion and PCM loss + centriole destruction (CD). The fly shares the PCM loss + CD mechanism of CE during late oogenesis that is dependent on downregulation of Polo kinase. In contrast to starfish, CE occurs prior to meiosis, resulting in acentrosomal meiosis. The mechanisms of CD remain unknown. Developmental Cell 2016 38, 10-12DOI: (10.1016/j.devcel.2016.06.027) Copyright © 2016 Terms and Conditions