Autophagy-Mediated Tumor Promotion

Slides:

Advertisements

Similar presentations

UpSET Recruits HDAC Complexes and Restricts Chromatin Accessibility and Acetylation at Promoter Regions Hector Rincon-Arano, Jessica Halow, Jeffrey J.

Advertisements

Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E Yumi Kim, Andrew J. Holland, Weijie Lan, Don W. Cleveland.

SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration Amit R. Reddi, Valeria C. Culotta Cell Volume 152, Issue 1, Pages (January.

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

The RAG Recombinase Dictates Functional Heterogeneity and Cellular Fitness in Natural Killer Cells Jenny M. Karo, David G. Schatz, Joseph C. Sun Cell Volume.

The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity Jenni Durieux, Suzanne Wolff, Andrew Dillin Cell Volume 144, Issue 1, Pages.

Local Translation of Extranuclear Lamin B Promotes Axon Maintenance Byung C. Yoon, Hosung Jung, Asha Dwivedy, Catherine M. O'Hare, Krishna H. Zivraj, Christine.

Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding J. Winter, M. Ilbert, P.C.F. Graf, D. Özcelik, U. Jakob Cell Volume 135, Issue.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Fatty Acid Trafficking in Starved Cells: Regulation by Lipid Droplet Lipolysis, Autophagy, and Mitochondrial Fusion Dynamics Angelika S. Rambold, Sarah.

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity Michael S. Rooney, Sachet A. Shukla, Catherine J. Wu, Gad Getz,

Growing Dendrites and Axons Differ in Their Reliance on the Secretory Pathway Bing Ye, Ye Zhang, Wei Song, Susan H. Younger, Lily Yeh Jan, Yuh Nung Jan.

Mitoconfusion: Noncanonical Functioning of Dynamism Factors in Static Mitochondria of the Heart Moshi Song, Gerald W. Dorn Cell Metabolism Volume 21, Issue.

Common Sense about Taste: From Mammals to Insects David A. Yarmolinsky, Charles S. Zuker, Nicholas J.P. Ryba Cell Volume 139, Issue 2, Pages (October.

UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke Jae Young Lee, Wei Yang Cell Volume 127, Issue 7, Pages (December.

Nucleation and Transport Organize Microtubules in Metaphase Spindles Jan Brugués, Valeria Nuzzo, Eric Mazur, Daniel J. Needleman Cell Volume 149, Issue.

Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell

Cancer Metabolism Cell Volume 148, Issue 3, (February 2012) DOI: /j.cell Copyright © 2012 Terms and Conditions Terms and Conditions.

Dynein Anchors Its mRNA Cargo after Apical Transport in the Drosophila Blastoderm Embryo Renald Delanoue, Ilan Davis Cell Volume 122, Issue 1, Pages

Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell

The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes Tae-Min Kim, Peter W. Laird, Peter J. Park Cell Volume 155, Issue.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.

The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: /j.cell Copyright © 2011 Terms and Conditions Terms and Conditions.

P120-Catenin Mediates Inflammatory Responses in the Skin Mirna Perez-Moreno, Michael A. Davis, Ellen Wong, H. Amalia Pasolli, Albert B. Reynolds, Elaine.

Fate Restriction and Multipotency in Retinal Stem Cells Lázaro Centanin, Burkhard Hoeckendorf, Joachim Wittbrodt Cell Stem Cell Volume 9, Issue 6, Pages.

Stable Kinesin and Dynein Assemblies Drive the Axonal Transport of Mammalian Prion Protein Vesicles Sandra E. Encalada, Lukasz Szpankowski, Chun-hong Xia,

Close Encounters of the Lysosome-Peroxisome Kind

Rejuvenation by Therapeutic Elimination of Senescent Cells

Serine Metabolism Links Tumor Suppression to the Epigenetic Landscape

Metastasis gets site specific

Unweaving the Autism Spectrum

Fatty Acid Metabolism Meets Organelle Dynamics

Interleukin-18: The Bouncer at the Mucosal Bar

Tumor Evolution: A Problem of Histocompatibility

Mapping Human Epigenomes

Autophagy: Paying Charon's Toll

Volume 26, Issue 1, Pages 1-2 (July 2014)

SIRT6 Puts Cancer Metabolism in the Driver’s Seat

Not All DDRs Are Created Equal: Non-Canonical DNA Damage Responses

Should I Stay or Should I Go: Neuromodulators of Behavioral States

Volume 154, Issue 1, Pages (July 2013)

In This Issue Cell Volume 158, Issue 5, (August 2014)

MicroRNAs and Parallel Stem Cell Lives

ER Stress in Dendritic Cells Promotes Cancer

Volume 152, Issue 1, (January 2013)

Entosis: It's a Cell-Eat-Cell World

Jennifer A. Philips, Joel D. Ernst Cell

Counting Motors by Force

The Role of the RNAi Machinery in Heterochromatin Formation

Tumor Self-Seeding: Bidirectional Flow of Tumor Cells

Volume 130, Issue 6, (September 2007)

Lung Cancer Resets the Liver’s Metabolic Clock

Interleukin-18: The Bouncer at the Mucosal Bar

Mitochondria and Cancer

Close Encounters of the Lysosome-Peroxisome Kind

Volume 143, Issue 6, (December 2010)

Making the Most from Changes in Life

Autophagy SEPArates Germline and Somatic Cells

Learning from the Uncontrollable

MicroRNA-155 Function in B Cells

Under Pressure: Stromal Fibroblasts Change Their Ways

Volume 163, Issue 4, (November 2015)

Co-opted integrin signaling in ErbB2-induced mammary tumor progression

Volume 163, Issue 2, (October 2015)

Macrophage Metabolism Shapes Angiogenesis in Tumors

There's a Time and a Place for MYCN

Volume 134, Issue 6, (September 2008)

In This Issue Cell Volume 145, Issue 3, (April 2011)

The Ups and Downs of Src Regulation: Tumor Suppression by Cbp

Volume 148, Issue 1, (January 2012)

Presentation transcript:

Autophagy-Mediated Tumor Promotion Jessie Yanxiang Guo, Bing Xia, Eileen White Cell Volume 155, Issue 6, Pages 1216-1219 (December 2013) DOI: 10.1016/j.cell.2013.11.019 Copyright © 2013 Elsevier Inc. Terms and Conditions

Figure 1 Role of Autophagy in Tumor Progression and Fate (A) Autophagy promotes mammary tumorigenesis induced by PALB2 loss. (B) Autophagy promotes the growth of KRASG12D-driven NSCLC. Lipid droplets are indicated in red, oncocytes are indicated in pink, and defective mitochondria are indicated in yellow. (C) Autophagy promotes BRAFV600E-induced lung tumor growth. Cell 2013 155, 1216-1219DOI: (10.1016/j.cell.2013.11.019) Copyright © 2013 Elsevier Inc. Terms and Conditions