Optimizing selection of patients for major lung resection

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Presentation transcript:

Optimizing selection of patients for major lung resection Mark K. Ferguson, MDa, Laurie B. Reeder, MDa (by invitation), Rosemarie Mick, MSb, c (by invitation) The Journal of Thoracic and Cardiovascular Surgery Volume 109, Issue 2, Pages 275-283 (February 1995) DOI: 10.1016/S0022-5223(95)70389-6 Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 1 The incidence of mortality (shaded bars), cardiac morbidity (open bars), pulmonary morbidity (cross-hatched bars), and overall morbidity (stippled bars) versus ppoDlco % (see text for explanation). Mortality and complications are inversely related to ppoDlco % (Cochran-Armitage trend test; p ≤ 0.004 for each). The Journal of Thoracic and Cardiovascular Surgery 1995 109, 275-283DOI: (10.1016/S0022-5223(95)70389-6) Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 2 The probability of mortality expressed as a function of ppoDlco % and ppoFEV1 %, where probability = 1/[1 +exp(-[0.703 -(0.0559 x ppoDlco %) - (0.00557 x ppoFEV1 %)])]. Left, A surface constructed by calculating the estimated probability of mortality using ppoDlco % and ppoFEV1 % data from 287 patients. Actual operative mortalities are indicated by black dots. Right, A theoretical surface of predicted risk of mortality generated by the equation alone demonstrates that almost all of the risk is dependent on ppoDlco %. The Journal of Thoracic and Cardiovascular Surgery 1995 109, 275-283DOI: (10.1016/S0022-5223(95)70389-6) Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 2 The probability of mortality expressed as a function of ppoDlco % and ppoFEV1 %, where probability = 1/[1 +exp(-[0.703 -(0.0559 x ppoDlco %) - (0.00557 x ppoFEV1 %)])]. Left, A surface constructed by calculating the estimated probability of mortality using ppoDlco % and ppoFEV1 % data from 287 patients. Actual operative mortalities are indicated by black dots. Right, A theoretical surface of predicted risk of mortality generated by the equation alone demonstrates that almost all of the risk is dependent on ppoDlco %. The Journal of Thoracic and Cardiovascular Surgery 1995 109, 275-283DOI: (10.1016/S0022-5223(95)70389-6) Copyright © 1995 Mosby, Inc. Terms and Conditions

Appendix Fig. 1. The probability of mortality expressed as a function of ppoDL co% and age, where probability = 1/[1 + exp(-[-4.033 - (0.0767 × ppoDlco%) + (0.0852 × age)])]. Left, A surface constructed by calculating the estimated probability of mortality usihg ppoDL co% and age data from 275 patients. Actual operative mortalites are indicated by black dots. Right, A theoretical surface of predicted risk of mortality generated using the equation only demonstrates the interaction of ppoDL co% and age in estimating risk. The Journal of Thoracic and Cardiovascular Surgery 1995 109, 275-283DOI: (10.1016/S0022-5223(95)70389-6) Copyright © 1995 Mosby, Inc. Terms and Conditions

Appendix Fig. 1. The probability of mortality expressed as a function of ppoDL co% and age, where probability = 1/[1 + exp(-[-4.033 - (0.0767 × ppoDlco%) + (0.0852 × age)])]. Left, A surface constructed by calculating the estimated probability of mortality usihg ppoDL co% and age data from 275 patients. Actual operative mortalites are indicated by black dots. Right, A theoretical surface of predicted risk of mortality generated using the equation only demonstrates the interaction of ppoDL co% and age in estimating risk. The Journal of Thoracic and Cardiovascular Surgery 1995 109, 275-283DOI: (10.1016/S0022-5223(95)70389-6) Copyright © 1995 Mosby, Inc. Terms and Conditions