On the Origin of the Term “Stem Cell”

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Presentation transcript:

On the Origin of the Term “Stem Cell” Miguel Ramalho-Santos, Holger Willenbring Cell Stem Cell Volume 1, Issue 1, Pages 35-38 (June 2007) DOI: 10.1016/j.stem.2007.05.013 Copyright © 2007 Elsevier Inc. Terms and Conditions

Figure 1 Early Uses of the Term “Stem Cell” (A) Valentin Häcker's 1892 diagram of the stem cell in the Cyclops embryo. According to Häcker, the stem cell (st) has just migrated to the inside of the embryo and is about to undergo asymmetric cell division. One daughter cell will give rise to the germline; the other will give rise to mesodermal tissue. (B) Artur Pappenheim's view of hematopoiesis from 1905. The cell in the center is the hypothesized common progenitor of the entire blood system. Pappenheim called this cell, among other terms, the stem cell. Cell Stem Cell 2007 1, 35-38DOI: (10.1016/j.stem.2007.05.013) Copyright © 2007 Elsevier Inc. Terms and Conditions